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Marcus S Niepel

Explore the profile of Marcus S Niepel including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 49
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Recent Articles
1.
Ekambaram B, Niepel M, Fuhrmann B, Schmidt G, Groth T
ACS Biomater Sci Eng . 2021 Jan; 4(5):1820-1832. PMID: 33445337
The extracellular matrix (ECM) is a nanostructured environment that provides chemical, mechanical, and topographical stimuli for various cellular functions. Here, we introduce the application of laser interference lithography (LIL) to...
2.
Niepel M, Ekambaram B, Schmelzer C, Groth T
Nanoscale . 2019 Jan; 11(6):2878-2891. PMID: 30688341
Laser interference lithography (LIL) and the layer-by-layer (LbL) technique are combined here for the first time to design a system with variable nanotopographies and surface viscoelasticity to regulate cell behavior....
3.
Niepel M, Almouhanna F, Ekambaram B, Menzel M, Heilmann A, Groth T
Int J Artif Organs . 2018 Mar; 41(4):223-235. PMID: 29528795
Background: Cells possess a specialized machinery through which they can sense physical as well as chemical alterations in their surrounding microenvironment that affect their cellular behavior. Aim: In this study,...
4.
Guduru D, Niepel M, Gonzalez-Garcia C, Salmeron-Sanchez M, Groth T
Macromol Biosci . 2017 May; 17(8). PMID: 28547877
Polyelectrolyte multilayer (PEM) coatings on biomaterials are applied to tailor adhesion, growth, and function of cells on biomedical implants. Here, biogenic and synthetic polyelectrolytes (PEL) are used for layer-by-layer assembly...
5.
Niepel M, Mano J, Groth T
ACS Appl Mater Interfaces . 2016 Sep; 8(38):25142-51. PMID: 27603547
Nanosphere lithography (NSL) and the layer-by-layer (LbL) technique are combined here for the first time to design a flexible system to achieve nanotopographical control of cell adhesion. NSL is used...
6.
Kowitsch A, Niepel M, Michanetzis G, Missirlis Y, Groth T
Macromol Biosci . 2015 Dec; 16(3):381-94. PMID: 26618787
Glycosaminoglycans (GAGs) chondroitin sulfate, heparin, hyaluronan, and sulfated hyaluronan are lower and higher thiolated to enable a one-step covalent modification of gold or vinyl-terminated surfaces. Measurements of water contact angle...
7.
Zhou G, Niepel M, Saretia S, Groth T
J Biomed Mater Res A . 2015 Oct; 104(2):493-502. PMID: 26458275
Chronic inflammatory responses after implantation of biomaterials can lead to fibrotic encapsulation and failure of implants. The present study was designed to reduce the inflammatory responses to biomaterials by assembling...
8.
Niepel M, Fuhrmann B, Leipner H, Groth T
Langmuir . 2013 Oct; 29(43):13278-90. PMID: 24090166
In general, there is a need for passivation of nanopatterned biomaterial surfaces if cells are intended to interact only with a feature of interest. For this reason self-assembled monolayers (SAM),...
9.
Niepel M, Peschel D, Groth T
Int J Artif Organs . 2011 Mar; 34(2):185-91. PMID: 21374559
Tissue cells need to adhere to a biomaterial surface to promote their growth and differentiation and, thus, foster the integration of implants. As a result, surface features and their modification...
10.
Niepel M, Peschel D, Sisquella X, Planell J, Groth T
Biomaterials . 2009 Jul; 30(28):4939-47. PMID: 19573910
Adhesion of tissue cells is a prerequisite for their growth and differentiation but prevents also apoptosis. Here the layer-by-layer technique (LbL) was used to design multilayer structures of poly(ethylene imine)...