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Marcus Grobe-Einsler

Explore the profile of Marcus Grobe-Einsler including associated specialties, affiliations and a list of published articles. Areas
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Citations 75
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Recent Articles
1.
Berger M, Garcia-Moreno H, Ferreira M, Hubener-Schmid J, Schaprian T, Wegner P, et al.
medRxiv . 2025 Feb; PMID: 39974031
Background: Spinocerebellar ataxia type 3 (SCA3) is an autosomal dominantly inherited adult-onset disease. We aimed to describe longitudinal changes in clinical and biological findings and to identify predictors for clinical...
2.
Lischewski S, Konrad K, Dogan I, Didszun C, Costa A, Schawohl S, et al.
Eur J Neurol . 2025 Jan; 32(1):e70011. PMID: 39797559
Background: Friedreich ataxia is a rare neurodegenerative disorder caused by frataxin deficiency. Both underweight and overweight occur in mitochondrial disorders, each with adverse health outcomes. We investigated the longitudinal evolution...
3.
Buchholz M, Pfaff M, Iskandar A, Reetz K, Schulz J, Grobe-Einsler M, et al.
Neurol Ther . 2024 Dec; 14(1):379-398. PMID: 39738982
Introduction: Friedreich Ataxia (FA) is a multisystem neurodegenerative disease. Affected individuals rely on mobility assistive technologies (MAT) (e.g. wheelchairs) and require long-term treatments and care. To analyse the patients' health-related...
4.
Elter T, Sturm D, Santana M, Schaprian T, Raposo M, Melo A, et al.
J Neurol . 2024 Dec; 272(1):54. PMID: 39666145
Introduction: Knowledge about the distribution and frequency of the respective haplotypes on the wildtype and mutant allele is highly relevant in the context of future gene therapy clinical studies in...
5.
Grobe-Einsler M, Baljasnikowa V, Faikus A, Schaprian T, Kaut O
Ann Clin Transl Neurol . 2024 Sep; 11(10):2673-2684. PMID: 39238196
Objective: To determine whether an accelerated protocol of 48 Hz cerebellar repetitive transcranial magnetic stimulation results in improved motor function in individuals with Parkinson's disease. Methods: In this double-blind randomized...
6.
Schmidt A, Danyel M, Grundmann K, Brunet T, Klinkhammer H, Hsieh T, et al.
Nat Genet . 2024 Jul; 56(8):1644-1653. PMID: 39039281
Individuals with ultrarare disorders pose a structural challenge for healthcare systems since expert clinical knowledge is required to establish diagnoses. In TRANSLATE NAMSE, a 3-year prospective study, we evaluated a...
7.
Grobe-Einsler M, Bork F, Faikus A, Hurlemann R, Kaut O
CNS Neurosci Ther . 2024 Jun; 30(6):e14797. PMID: 38887169
Background: In absence of drug therapy options, standard treatment for spinocerebellar ataxia consists of symptomatic physiotherapy and speech therapy. New therapeutic options are urgently needed. Transcranial magnetic stimulation is a...
8.
Grobe-Einsler M, Bork F, Faikus A, Neggers S, Kaut O
NeuroRehabilitation . 2024 Jun; 54(4):691-698. PMID: 38875051
Background: Cerebellar ataxia, neuropathy and bilateral vestibular areflexia (CANVAS) is a rare neurodegenerative disease affecting the cerebellum, the peripheral nervous system and the vestibular system. Due to the lack of...
9.
Grobe-Einsler M, Lupa A, Weller J, Kaut O
Neurorehabil Neural Repair . 2024 May; 38(7):539-550. PMID: 38804539
Background: Repetitive transcranial magnetic stimulation (rTMS) is a nonpharmacological and noninvasive brain stimulation technique that has been proven to be effective in Parkinson's disease (PD). The combination of rTMS and...
10.
Turski G, Turski C, Grobe-Einsler M, Kobeleva X, Turski J, Holz F, et al.
Restor Neurol Neurosci . 2024 Jan; 41(5-6):229-239. PMID: 38217556
Background: Hereditary spastic paraplegia (HSP) is characterized by progressive degeneration of distal axons in the long corticospinal tracts. Loss of retinal cells and microvascular networks has neither been suspected nor...