Alpha 2.0
Login Register
» Authors » Marcus Buggert

Marcus Buggert

Explore the profile of Marcus Buggert including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 104
Citations 4150
Followers 0
Related Specialties
Allergy & Immunology
General Medicine
Science
Top 10 Co-Authors
Hans-Gustaf Ljunggren
Soo Aleman
Johan K Sandberg
Annika C Karlsson
Puran Chen
Michael R Betts
Yu Gao
Peter Bergman
Piotr Nowak
David A Price
Published In
Sci Immunol
Front Immunol
Proc Natl Acad Sci U S A
Nat Immunol
Nat Commun
Affiliations
Soon will be listed here.
Recent Articles
1.
Deciphering immune predictors of immunotherapy response: A multiomics approach at the pan-cancer level
Li X, Pan L, Li W, Liu B, Xiao C, Chew V, et al.
Cell Rep Med . 2025 Mar; :101992. PMID: 40054456
Immune checkpoint blockade (ICB) therapy has transformed cancer treatment, yet many patients fail to respond. Employing single-cell multiomics, we unveil T cell dynamics influencing ICB response across 480 pan-cancer and...
2.
Antigen-specific T cell responses following single and co-administration of tick-borne encephalitis, Japanese encephalitis, and yellow fever virus vaccines: Results from an open-label, non-randomized clinical trial-cohort
Wullimann D, Sandberg J, Akber M, Lofling M, Gredmark-Russ S, Michaelsson J, et al.
PLoS Negl Trop Dis . 2025 Feb; 19(2):e0012693. PMID: 40019865
Background: Flavivirus infections pose a significant global health burden, highlighting the need for safe and effective vaccination strategies. Co-administration of different vaccines, including licensed flavivirus vaccines, is commonly practiced providing...
3.
Targeting the SARS-CoV-2 reservoir in long COVID
Proal A, Aleman S, Bomsel M, Brodin P, Buggert M, Cherry S, et al.
Lancet Infect Dis . 2025 Feb; PMID: 39947217
There are no approved treatments for post-COVID-19 condition (also known as long COVID), a debilitating disease state following SARS-CoV-2 infection that is estimated to affect tens of millions of people....
4.
Human MAIT cell response profiles biased toward IL-17 or IL-10 are distinct effector states directed by the cytokine milieu
Boulouis C, Mouchtaridi E, Muller T, Mak J, Fairlie D, Bergman P, et al.
Proc Natl Acad Sci U S A . 2025 Feb; 122(6):e2414230122. PMID: 39903121
Mucosal-associated invariant T (MAIT) cells are unconventional T cells that mediate rapid antimicrobial immune responses to antigens derived from microbial riboflavin pathway metabolites presented by the evolutionarily conserved MR1 molecules....
5.
Unlocking novel T cell-based immunotherapy for hepatocellular carcinoma through neoantigen-driven T cell receptor isolation
Maravelia P, Yao H, Cai C, Silva D, Fransson J, Nilsson O, et al.
Gut . 2025 Jan; PMID: 39832892
Background: Tumour-infiltrating T cells can mediate both antitumour immunity and promote tumour progression by creating an immunosuppressive environment. This dual role is especially relevant in hepatocellular carcinoma (HCC), characterised by...
6.
Real-world assessment of immunogenicity in immunocompromised individuals following SARS-CoV-2 mRNA vaccination: a two-year follow-up of the prospective clinical trial COVAXID
Chen P, Bergman P, Blennow O, Hansson L, Mielke S, Nowak P, et al.
EBioMedicine . 2024 Oct; 109:105385. PMID: 39395230
Background: Immunocompromised patients with primary and secondary immunodeficiencies have shown impaired responses to SARS-CoV-2 mRNA vaccines, necessitating recommendations for additional booster doses. However, longitudinal data reflecting the real-world impact of...
7.
The epigenomic matrix of tissue-specific immune memory
Adamo S, Buggert M
Immunity . 2024 Sep; 57(9):2007-2009. PMID: 39260353
Tissue-resident memory CD8 T cells serve as a first-line defense against many pathogens. In this issue of Immunity, Buquicchio et al. unveil the epigenomic landscapes of virus-specific CD8 T cell...
8.
MAIT cell heterogeneity across paired human tissues reveals specialization of distinct regulatory and enhanced effector profiles
Kammann T, Cai C, Sekine T, Mouchtaridi E, Boulouis C, Nilsen V, et al.
Sci Immunol . 2024 Sep; 9(99):eadn2362. PMID: 39241054
Mucosal-associated invariant T (MAIT) cells are unconventional T cells that recognize microbial riboflavin pathway metabolites presented by evolutionarily conserved MR1 molecules. We explored the human MAIT cell compartment across organ...
9.
Combination anti-PD-1 and anti-CTLA-4 therapy generates waves of clonal responses that include progenitor-exhausted CD8 T cells
Wang K, Coutifaris P, Brocks D, Wang G, Azar T, Solis S, et al.
Cancer Cell . 2024 Aug; 42(9):1582-1597.e10. PMID: 39214097
Combination checkpoint blockade with anti-PD-1 and anti-CTLA-4 antibodies has shown promising efficacy in melanoma. However, the underlying mechanism in humans remains unclear. Here, we perform paired single-cell RNA and T ...
10.
Severe Tick-Borne Encephalitis (TBE) in a Patient with X-Linked Agammaglobulinemia; Treatment with TBE Virus IgG Positive Plasma, Clinical Outcome and T Cell Responses
Hedin W, Bergman P, Akhirunessa M, Soderholm S, Buggert M, Granberg T, et al.
J Clin Immunol . 2024 Apr; 44(5):116. PMID: 38676861
Purpose: A patient with X-linked agammaglobulinemia (XLA) and severe tick-borne encephalitis (TBE) was treated with TBE virus (TBEV) IgG positive plasma. The patient's clinical response, humoral and cellular immune responses...