Marcos S Lopes
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Explore the profile of Marcos S Lopes including associated specialties, affiliations and a list of published articles.
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25
Citations
427
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Recent Articles
1.
Boshove A, Derks M, Sevillano C, Lopes M, van Son M, Knol E, et al.
PLoS Genet
. 2024 Jan;
20(1):e1011034.
PMID: 38198533
Most deleterious variants are recessive and segregate at relatively low frequency. Therefore, high sample sizes are required to identify these variants. In this study we report a large-scale sequence based...
2.
Duenk P, Wientjes Y, Bijma P, Iversen M, Lopes M, Calus M
Genet Sel Evol
. 2023 Jan;
55(1):2.
PMID: 36639760
Background: The genetic correlation between purebred (PB) and crossbred (CB) performances ([Formula: see text]) partially determines the response in CB when selection is on PB performance in the parental lines....
3.
Sell-Kubiak E, Dobrzanski J, Derks M, Lopes M, Szwaczkowski T
Genes (Basel)
. 2022 Oct;
13(10).
PMID: 36292615
Nearly 2000 SNPs associated with pig litter size traits have been reported based on genome-wide association studies (GWASs). The aims of this study were to gather and integrate previously reported...
4.
Oliveira H, Derks M, Lopes M, Madsen O, Harlizius B, van Son M, et al.
Front Genet
. 2022 Jun;
13:871516.
PMID: 35692822
Backfat is an important trait in pork production, and it has been included in the breeding objectives of genetic companies for decades. Although adipose tissue is a good energy storage,...
5.
Derks M, Gross C, Lopes M, Reinders M, Bosse M, Gjuvsland A, et al.
Genomics
. 2021 May;
113(4):2229-2239.
PMID: 34022350
The genotype-phenotype link is a major research topic in the life sciences but remains highly complex to disentangle. Part of the complexity arises from the number of genes contributing to...
6.
Botelho M, Lopes M, Mathur P, Knol E, Guimaraes S, Marques D, et al.
J Anim Breed Genet
. 2020 Dec;
138(4):442-453.
PMID: 33285013
Biological information regarding markers and gene association may be used to attribute different weights for single nucleotide polymorphism (SNP) in genome-wide selection. Therefore, we aimed to evaluate the predictive ability...
7.
Derks M, Harlizius B, Lopes M, Greijdanus-van der Putten S, Dibbits B, Laport K, et al.
Front Genet
. 2019 Dec;
10:1226.
PMID: 31850074
Piglet mortality is a complex phenotype that depends on the environment, selection on piglet health, but also on the interaction between the piglet and sow. However, also monogenic recessive defects...
8.
Godinho R, Bergsma R, Silva F, Sevillano C, Knol E, Komen H, et al.
J Anim Sci
. 2019 Jul;
97(9):3648-3657.
PMID: 31278865
In pig breeding, selection commonly takes place in purebred (PB) pigs raised mainly in temperate climates (TEMP) under optimal environmental conditions in nucleus farms. However, pork production typically makes use...
9.
van den Berg S, Vandenplas J, van Eeuwijk F, Lopes M, Veerkamp R
J Anim Breed Genet
. 2019 Jun;
136(6):418-429.
PMID: 31215703
Significance testing for genome-wide association study (GWAS) with increasing SNP density up to whole-genome sequence data (WGS) is not straightforward, because of strong LD between SNP and population stratification. Therefore,...
10.
van Son M, Lopes M, Martell H, Derks M, Gangsei L, Kongsro J, et al.
Front Genet
. 2019 Apr;
10:272.
PMID: 30972109
Modern breeding schemes for livestock species accumulate a large amount of genotype and phenotype data which can be used for genome-wide association studies (GWAS). Many chromosomal regions harboring effects on...