Marco Mandolesi
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Explore the profile of Marco Mandolesi including associated specialties, affiliations and a list of published articles.
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9
Citations
87
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Recent Articles
1.
Wang H, Cheng C, Dal Santo J, Shen C, Bylund T, Henry A, et al.
Cell
. 2024 Oct;
187(25):7214-7231.e23.
PMID: 39471811
An antibody-based HIV-1 vaccine will require the induction of potent cross-reactive HIV-1-neutralizing responses. To demonstrate feasibility toward this goal, we combined vaccination targeting the fusion-peptide site of vulnerability with infection...
2.
Mandolesi M, Das H, de Vries L, Yang Y, Kim C, Dhinakaran M, et al.
Nat Commun
. 2024 Jul;
15(1):6338.
PMID: 39068149
The continued evolution of SARS-CoV-2 underscores the need to understand qualitative aspects of the humoral immune response elicited by spike immunization. Here, we combine monoclonal antibody (mAb) isolation with deep...
3.
Dopico X, Guryleva M, Mandolesi M, Corcoran M, Coquet J, Murrell B, et al.
Clin Transl Immunology
. 2024 May;
13(5):e1508.
PMID: 38707998
Objectives: The caecum bridges the small and large intestine and plays a front-line role in discriminating gastrointestinal antigens. Although dysregulated in acute and chronic conditions, the tissue is often overlooked...
4.
Dopico X, Mandolesi M, Karlsson Hedestam G
Immunol Lett
. 2023 May;
259:24-29.
PMID: 37209913
Immunoglobulin (IG) genes, encoding B cell receptors (BCRs), are fundamental components of the mammalian immune system, which evolved to recognize the diverse antigenic universe present in nature. To handle these...
5.
Corcoran M, Chernyshev M, Mandolesi M, Narang S, Kaduk M, Ye K, et al.
Immunity
. 2023 Feb;
56(3):635-652.e6.
PMID: 36796364
Human T cell receptors (TCRs) are critical for mediating immune responses to pathogens and tumors and regulating self-antigen recognition. Yet, variations in the genes encoding TCRs remain insufficiently defined. Detailed...
6.
Mandolesi M, Rodahl I, Steiner L, Gronwall C, Smed-Sorensen A
Scand J Immunol
. 2022 Mar;
95(6):e13161.
PMID: 35298038
No abstract available.
7.
Sheward D, Mandolesi M, Urgard E, Kim C, Hanke L, Perez Vidakovics L, et al.
Cell Rep Med
. 2021 Nov;
2(11):100450.
PMID: 34723224
Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) with resistance to neutralizing antibodies are threatening to undermine vaccine efficacy. Vaccination and infection have led to widespread humoral immunity...
8.
Mandolesi M, Sheward D, Hanke L, Ma J, Pushparaj P, Perez Vidakovics L, et al.
Cell Rep Med
. 2021 Apr;
2(4):100252.
PMID: 33842900
The outbreak and spread of SARS-CoV-2 (severe acute respiratory syndrome-coronavirus-2) is a current global health emergency, and effective prophylactic vaccines are needed urgently. The spike glycoprotein of SARS-CoV-2 mediates entry...
9.
Jabs F, Plum M, Laursen N, Jensen R, Molgaard B, Miehe M, et al.
Nat Commun
. 2018 Jan;
9(1):7.
PMID: 29295972
Anti-IgE therapeutics interfere with the ability of IgE to bind to its receptors on effector cells. Here we report the crystal structure of an anti-IgE single-domain antibody in complex with...