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Marcin Wierzchowski

Explore the profile of Marcin Wierzchowski including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 263
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Recent Articles
1.
Pajzderska A, Wierzchowski M, Lazewski D, Gielara-Korzanska A, Korzanski A, Popenda L, et al.
Phys Chem Chem Phys . 2023 Jul; 25(27):18481-18494. PMID: 37401852
The methoxy analogue of a -stilbene compound - 2,3,3',4'-tetramethoxy--stilbene - was selected to characterize its crystallographic structure, intermolecular interactions and molecular dynamics. The sample was studied using single-crystal X-ray diffraction...
2.
Piekus-Slomka N, Malecka M, Wierzchowski M, Kupcewicz B
Int J Mol Sci . 2023 Apr; 24(8). PMID: 37108369
In recent years, fluorescent compounds that emit efficiently in the solid state have become particularly interesting, especially those that are easily prepared and inexpensive. Hence, exploring the photophysical properties of...
3.
Lazewski D, Kucinska M, Potapskiy E, Kuzminska J, Popenda L, Tezyk A, et al.
Int J Mol Sci . 2023 Jan; 24(2). PMID: 36674983
Curcumin has been modified in various ways to broaden its application in medicine and address its limitations. In this study, we present a series of curcumin-based derivatives obtained by replacing...
4.
Kobylka P, Kucinska M, Kujawski J, Lazewski D, Wierzchowski M, Murias M
Molecules . 2022 Oct; 27(20). PMID: 36296565
Resveratrol is a plant-derived phytoalexin found in grapes, red wine and many other plants used in Asian folk medicine. It is extensively studied for pleiotropic biological activity. The most crucial...
5.
Lazewski D, Kucinska M, Potapskiy E, Kuzminska J, Tezyk A, Popenda L, et al.
Int J Mol Sci . 2022 Sep; 23(17). PMID: 36077451
This work presents the synthesis and characterization of metal-free, zinc (II), and cobalt (II) porphyrins substituted with short PEG chains. The synthesized compounds were characterized by UV-Vis, H and C...
6.
Nowicki A, Wawrzyniak D, Czajkowski M, Jozkowiak M, Pawlak M, Wierzchowski M, et al.
Drug Deliv . 2022 Jul; 29(1):2459-2468. PMID: 35892260
3'-hydroxy-3,4,5,4'-tetramethoxystilbene (DMU-214) belongs to methoxystilbenes family and is an active metabolite of 3,4,5,4'-tetramethoxystilbene (DMU-212). In several of our previous studies, the anti-apoptotic activity of DMU-214 was significantly higher than that...
7.
Wierzchowski M, Ziental D, Lazewski D, Korzanski A, Gielara-Korzanska A, Tykarska E, et al.
Int J Mol Sci . 2022 Jun; 23(11). PMID: 35682587
Newly developed tetra- and octasubstituted methimazole-phthalocyanine conjugates as potential photosensitizers have been obtained. Synthesized intermediates and final products were characterized by the MALD-TOF technique and various NMR techniques, including 2D...
8.
Jozkowiak M, Dyszkiewicz-Konwinska M, Ramlau P, Kranc W, Spaczynska J, Wierzchowski M, et al.
Int J Mol Sci . 2021 Jul; 22(12). PMID: 34201116
The methylated resveratrol analogue 3'-hydroxy-3,4,5,4'-tetramethoxystilbene (DMU-214) has been revealed to exert the anti-cancer activity by a block of the cell cycle at the G2/M phase, apoptosis induction, and metastasis inhibition....
9.
Majchrzak-Celinska A, Zielinska-Przyjemska M, Wierzchowski M, Kleszcz R, Studzinska-Sroka E, Kaczmarek M, et al.
Adv Med Sci . 2020 Nov; 66(1):6-20. PMID: 33238230
Purpose: Glioblastoma is the most common and the deadliest brain cancer. The aim of this study was to analyze the impact of resveratrol and its five analogs: 3,4,4'-trimethoxy, 3,4,2'-trimethoxy, 3,4,2',4'-tetramethoxy,...
10.
Zielinska-Przyjemska M, Kaczmarek M, Krajka-Kuzniak V, Wierzchowski M, Baer-Dubowska W
Mol Cell Biochem . 2020 Aug; 474(1-2):113-123. PMID: 32737773
The present study aimed to evaluate the cytotoxicity and its mechanism of five synthetic methoxy stilbenes, namely 3,4,4'-trimethoxy, 3,4,2'-trimethoxy, 3,4,2',4'-tetramethoxy, 3,4,2',6'-tetramethoxy, and 3,4,2',4',6'-pentamethoxy-trans-stilbenes (MS), in comparison with resveratrol (RSV). Human...