Marc Thilo Figge
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Explore the profile of Marc Thilo Figge including associated specialties, affiliations and a list of published articles.
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118
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1810
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Recent Articles
1.
Praetorius J, Hitzler S, Gresnigt M, Figge M
FEMS Yeast Res
. 2025 Mar;
PMID: 40082735
The formation of hyphae is one of the most crucial virulence traits the human pathogenic fungus Candida albicans possesses. The assessment of hyphal length in response to various stimuli, such...
2.
Koceva H, Amiratashani M, Akbarimoghaddam P, Hoffmann B, Zhurgenbayeva G, Gresnigt M, et al.
Open Biol
. 2025 Mar;
15(3):240231.
PMID: 40037530
The lung microbiome has recently gained attention for potentially affecting respiratory viral infections, including influenza A virus, respiratory syncytial virus (RSV) and SARS-CoV-2. We will discuss the complexities of the...
3.
Lossius-Cott C, Annoh A, Bens M, Nietzsche S, Hoffmann B, Figge M, et al.
JBMR Plus
. 2025 Feb;
9(3):ziae173.
PMID: 39906260
Activating internal tandem duplications (ITD) in the juxtamembrane domain of receptor tyrosine kinase FLT3 occur frequently in patients with acute myeloid leukemia (AML). Constitutive active FLT3-ITD mutations induce aberrant signaling...
4.
Abou-Kandil A, Troger-Gorler S, Pschibul A, Kruger T, Rosin M, Schmidt F, et al.
Microlife
. 2025 Jan;
6:uqae024.
PMID: 39790482
The polyene antimycotic amphotericin B (AmB) and its liposomal formulation AmBisome belong to the treatment options of invasive aspergillosis caused by . Increasing resistance to AmB in clinical isolates of...
5.
Xiong L, Beyer D, Liu N, Lehmann T, Neugebauer S, Schaeuble S, et al.
Pharmacol Res
. 2025 Jan;
212:107581.
PMID: 39761839
Sepsis is a life-threatening organ failure resulting from a poorly regulated infection response. Organ dysfunction includes hepatic involvement, weakening the immune system due to excretory liver failure, and metabolic dysfunction,...
6.
Visser C, Rivieccio F, Kruger T, Schmidt F, Cseresnyes Z, Rohde M, et al.
Microlife
. 2024 Dec;
5:uqae022.
PMID: 39660046
Extracellular vesicles (EVs) have gained attention as facilitators of intercellular as well as interkingdom communication during host-microbe interactions. Recently we showed that upon infection, host polymorphonuclear leukocytes produce antifungal EVs...
7.
Saffer C, Timme S, Ortiz S, Bertuzzi M, Figge M
Commun Biol
. 2024 Dec;
7(1):1615.
PMID: 39632928
The human lung is confronted daily with thousands of microbial invaders reaching the lower respiratory tract. An efficient response by the resident type 1 and type 2 alveolar epithelial cells...
8.
Liu N, Sonawane M, Sommerfeld O, Svensson C, Figge M, Bauer R, et al.
Front Immunol
. 2024 Sep;
15:1432307.
PMID: 39281680
Background: Limited availability and side effects of opioids have led to an increased use of non-opioid analgesia in animal disease models. However, by affecting the immune-inflammatory reactions, analgesia may disrupt...
9.
Gunther K, Nischang V, Cseresnyes Z, Kruger T, Sheta D, Abboud Z, et al.
Immunology
. 2024 Sep;
173(4):748-767.
PMID: 39268960
Gliotoxin (GT), a secondary metabolite and virulence factor of the fungal pathogen Aspergillus fumigatus, suppresses innate immunity and supports the suppression of host immune responses. Recently, we revealed that GT...
10.
Chamas A, Svensson C, Maneira C, Sporniak M, Figge M, Lackner G
ACS Synth Biol
. 2024 Sep;
13(12):4027-4039.
PMID: 39265099
Engineering live biotherapeutic products against fungal pathogens such as has been suggested as a means to tackle the increasing threat of fungal infections and the development of resistance to classical...