Marc S Horwitz
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Explore the profile of Marc S Horwitz including associated specialties, affiliations and a list of published articles.
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54
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968
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Recent Articles
1.
Allanach J, Fettig N, Hardman B, Rosen A, Fan V, Chung C, et al.
Sci Adv
. 2025 Mar;
11(10):eadu5110.
PMID: 40043135
Latent infection with Epstein-Barr virus (EBV) is a strong risk factor for the development of multiple sclerosis (MS), although the underlying mechanisms remain unclear. To investigate this association, we induced...
2.
Dunn S, Correale J, Gommerman J, Horwitz M
Front Immunol
. 2024 Jan;
14:1361884.
PMID: 38292480
No abstract available.
3.
Morse Z, Simister R, Crowe S, Horwitz M, Osborne L
Front Immunol
. 2023 Feb;
14:1096323.
PMID: 36742327
Autoimmune disorders are complex diseases of unclear etiology, although evidence suggests that the convergence of genetic susceptibility and environmental factors are critical. In type 1 diabetes (T1D), enterovirus infection and...
4.
Mouat I, Shanina I, Horwitz M
Sci Rep
. 2022 Dec;
12(1):21189.
PMID: 36477199
Age-associated B cells (ABCs; CD19CD11cT-bet) are a unique population that are increased in an array of viral infections, though their role during latent infection is largely unexplored. Here, we use...
5.
Mouat I, Allanach J, Fettig N, Fan V, Girard A, Shanina I, et al.
Sci Adv
. 2022 Nov;
8(47):eade6844.
PMID: 36427301
While age-associated B cells (ABCs) are known to expand and persist following viral infection and during autoimmunity, their interactions are yet to be studied together in these contexts. Here, we...
6.
Fettig N, Robinson H, Allanach J, Davis K, Simister R, Wang E, et al.
Cell Rep
. 2022 Sep;
40(11):111328.
PMID: 36103823
Dietary fibers are potent modulators of immune responses that can restrain inflammation in multiple disease contexts. However, dietary fibers encompass a biochemically diverse family of carbohydrates, and it remains unknown...
7.
Skovso S, Overby P, Memar-Zadeh J, Lee J, Yang J, Shanina I, et al.
Endocrinology
. 2022 Sep;
163(11).
PMID: 36048448
A central goal of physiological research is the understanding of cell-specific roles of disease-associated genes. Cre-mediated recombineering is the tool of choice for cell type-specific analysis of gene function in...
8.
Mouat I, Goldberg E, Horwitz M
Cell Mol Life Sci
. 2022 Jul;
79(8):402.
PMID: 35798993
Age-associated B cells (ABCs) are a transcriptionally and functionally unique B cell population. In addition to arising with age and following infection, ABCs are expanded during autoimmune disease, including those...
9.
Mouat I, Horwitz M
PLoS Pathog
. 2022 Mar;
18(3):e1010297.
PMID: 35298565
Age-associated B cells (ABCs) are a recently identified, unique B cell population that displays both protective and pathogenic characteristics, depending on the context. A major role of ABCs is to...
10.
Lincez P, Shanina I, Horwitz M
Front Immunol
. 2021 Nov;
12:751341.
PMID: 34804036
Seemingly redundant in function, melanoma differentiation-associated protein 5 (MDA5) and toll-like receptor- 3 (TLR3) both sense RNA viruses and induce type I interferon (IFN-I). Herein, we demonstrate that changes in...