Marc Hetzel
Overview
Explore the profile of Marc Hetzel including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
165
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0
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Recent Articles
1.
Flemmig T, Hetzel M, Topoll H, Gerss J, Haeberlein I, Petersilka G
J Periodontol
. 2007 Jun;
78(6):1002-10.
PMID: 17539712
Background: Glycine powder air polishing (GPAP) has been shown to be significantly more effective in reducing the subgingival cultivable microflora in shallow periodontal pockets compared to curets and is safe...
2.
Buckel W, Hetzel M, Kim J
Curr Opin Chem Biol
. 2004 Sep;
8(5):462-7.
PMID: 15450487
A novel method to generate organic radicals in enzymatic reactions is described, which is similar to electron transfer in nitrogenase. Component A of 2-hydroxyglutaryl-CoA dehydratase contains a [4Fe-4S] cluster located...
3.
Kim J, Hetzel M, Boiangiu C, Buckel W
FEMS Microbiol Rev
. 2004 Sep;
28(4):455-68.
PMID: 15374661
Several clostridia and fusobacteria ferment alpha-amino acids via (R)-2-hydroxyacyl-CoA, which is dehydrated to enoyl-CoA by syn-elimination. This reaction is of great mechanistic interest, since the beta-hydrogen, to be eliminated as...
4.
Hetzel M, Brock M, Selmer T, Pierik A, Golding B, Buckel W
Eur J Biochem
. 2003 Feb;
270(5):902-10.
PMID: 12603323
Acryloyl-CoA reductase from Clostridium propionicum catalyses the irreversible NADH-dependent formation of propionyl-CoA from acryloyl-CoA. Purification yielded a heterohexadecameric yellow-greenish enzyme complex [(alpha2betagamma)4; molecular mass 600 +/- 50 kDa] composed of...
5.
Hans M, Bill E, Cirpus I, Pierik A, Hetzel M, Alber D, et al.
Biochemistry
. 2002 May;
41(18):5873-82.
PMID: 11980491
2-hydroxyglutaryl-CoA dehydratase from Acidaminococcus fermentans catalyzes the chemical difficult elimination of water from (R)-2-hydroxyglutaryl-CoA to glutaconyl-CoA. The enzyme consists of two oxygen-sensitive protein components, the homodimeric activator (A) with one...
6.
Selmer T, Willanzheimer A, Hetzel M
Eur J Biochem
. 2002 Jan;
269(1):372-80.
PMID: 11784332
Propionate CoA-transferase from Clostridium propionicum has been purified and the gene encoding the enzyme has been cloned and sequenced. The enzyme was rapidly and irreversibly inactivated by sodium borohydride or...