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Marc A Schneider

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Articles 59
Citations 1450
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Recent Articles
11.
Sikosek T, Horos R, Trudzinski F, Jehn J, Frank M, Rajakumar T, et al.
J Thorac Oncol . 2023 Jul; 18(11):1504-1523. PMID: 37437883
Introduction: Lung cancer remains the deadliest cancer in the world, and lung cancer survival is heavily dependent on tumor stage at the time of detection. Low-dose computed tomography screening can...
12.
Theobald V, Grunig E, Benjamin N, Seyfarth H, Halank M, Schneider M, et al.
Pulm Circ . 2023 Jun; 13(2):e12242. PMID: 37292089
Iron deficiency is common in idiopathic and heritable pulmonary arterial hypertension patients (I/HPAH). A previous report suggested a dysregulation of the iron hormone hepcidin, which is controlled by BMP/SMAD signaling...
13.
Dragani T, Muley T, Schneider M, Kobinger S, Eichhorn M, Winter H, et al.
Cancers (Basel) . 2023 May; 15(8). PMID: 37190323
To date, the factors which affect the age at diagnosis of lung adenocarcinoma are not fully understood. In our study, we examined the relationships of age at diagnosis with smoking,...
14.
Schwartz U, Llamazares Prada M, Pohl S, Richter M, Tamas R, Schuler M, et al.
EMBO J . 2023 May; 42(12):e111272. PMID: 37143403
Patients with chronic obstructive pulmonary disease (COPD) are still waiting for curative treatments. Considering its environmental cause, we hypothesized that COPD will be associated with altered epigenetic signaling in lung...
15.
Angeles A, Janke F, Daum A, Reck M, Schneider M, Thomas M, et al.
Br J Cancer . 2023 Apr; 129(1):112-121. PMID: 37120670
Background: Detection of circulating tumour DNA (ctDNA) in biological fluids is a minimally invasive alternative to tissue biopsy for therapy monitoring. Cytokines are released in the tumour microenvironment to influence...
16.
Janke F, Angeles A, Riediger A, Bauer S, Reck M, Stenzinger A, et al.
Clin Epigenetics . 2022 Dec; 14(1):163. PMID: 36461127
Background: DNA methylation (5-mC) signals in cell-free DNA (cfDNA) of cancer patients represent promising biomarkers for minimally invasive tumor detection. The high abundance of cancer-associated 5-mC alterations permits parallel and...
17.
Bozorgmehr F, Christopoulos P, Chung I, Cvetkovic J, Feisst M, Krisam J, et al.
BMC Cancer . 2022 Sep; 22(1):1011. PMID: 36153496
Background: Recently, the combination of the programmed death-ligand 1 (PD-L1) inhibitor atezolizumab with first-line chemotherapy has demonstrated to improve outcome for patients with advanced small cell lung cancer (SCLC), leading...
18.
Grunding A, Schneider M, Richtmann S, Kriegsmann M, Winter H, Martinez-Delgado B, et al.
Cancers (Basel) . 2022 Sep; 14(18). PMID: 36139614
To explore the relationship between cancer cell SREBF1 expression, lipid droplets (LDs) formation, and the sensitivity to chemotherapies, we cultured lung adenocarcinoma cells H1299 (with LD) and H1563 (without LD)...
19.
Trefzer T, Schneider M, Jechow K, Chua R, Muley T, Winter H, et al.
Cancer Res . 2022 Jul; 82(17):3116-3129. PMID: 35819252
Single-cell analysis of healthy lung tissue and lung cancer reveals distinct tumor cell populations, including cells with differential immune modulating capacity between smokers and never smokers, which could guide future...
20.
Theobald V, Benjamin N, Seyfarth H, Halank M, Schneider M, Richtmann S, et al.
Genes (Basel) . 2022 May; 13(5). PMID: 35627145
Pulmonary arterial hypertension (PAH) can be caused by pathogenic variants in the gene bone morphogenetic protein receptor 2 (BMPR2). While BMPR2 protein expression levels are known to be reduced in...