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Maoxiang Qian

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Articles 53
Citations 1065
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Recent Articles
11.
Xing Z, Zhu X, Li Z, Wang H, Qian M, Zhai X
Front Oncol . 2022 Sep; 12:989366. PMID: 36059682
Background: Myeloid sarcoma (MS) is a rare hematological tumor that presents with extramedullary tumor masses comprising myeloid blasts. A controversial issue is whether MS involving normal hematopoietic sites (liver, spleen,...
12.
Su N, Li Z, Yang J, Fu Y, Zhu X, Miao H, et al.
Front Oncol . 2022 Aug; 12:915833. PMID: 36003795
Pediatric acute megakaryoblastic leukemia (AMKL) is a subtype of acute myeloid leukemia (AML) characterized by abnormal megakaryoblasts, and it is divided into the AMKL patients with Down syndrome (DS-AMKL) and...
13.
Qu Y, Sun Z, Yuan Y, Li Z, Wang F, Wu K, et al.
Cell Death Dis . 2022 Jul; 13(7):620. PMID: 35851002
Aplastic anemia (AA) is a blood disorder resulted from over-activated T-cell related hematopoietic failure, with the characterization of hypocellularity and enhanced adipogenic differentiation of mesenchymal stroma cells (MSCs) in bone...
14.
Hao L, Ma J, Wu F, Ma X, Qian M, Sheng W, et al.
Clin Transl Med . 2022 Jul; 12(7):e941. PMID: 35808830
Background: Congenital heart disease (CHD) is the most common birth defect and has high heritability. Although some susceptibility genes have been identified, the genetic basis underlying the majority of CHD...
15.
Man J, Wang H, Qian X, Chen L, Ma Y, Qian M, et al.
Leuk Lymphoma . 2022 May; 63(10):2453-2460. PMID: 35617527
This retrospective single-center study was to evaluate the expression of TCF3 protein in pediatric Burkitt lymphomas (pBLs) and analyze its relations with clinical characteristics and prognosis. A total of 58...
16.
Zhao X, Qian M, Goodings C, Zhang Y, Yang W, Wang P, et al.
J Natl Cancer Inst . 2022 May; 114(9):1287-1295. PMID: 35575404
Background: There is growing evidence for the inherited basis of susceptibility to childhood acute lymphoblastic leukemia (ALL). Genome-wide association studies have identified non-coding ALL risk variants at the ARID5B gene...
17.
He Y, Zhang J, Zhang Y, Hu Z, Wang P, Gan W, et al.
Pediatr Blood Cancer . 2022 Apr; 69(8):e29724. PMID: 35441457
The prognosis of patients with T-cell acute lymphoblastic leukemia (T-ALL) has been largely lacked behind than that of patients with B-cell ALL, especially in refractory or relapsed cases. Here, we...
18.
He H, Li Z, Lu J, Qiang W, Jiang S, Xu Y, et al.
Clin Transl Med . 2022 Mar; 12(3):e757. PMID: 35297204
Background: Multiple myeloma (MM) is a clinically and biologically heterogeneous plasma-cell malignancy. Despite extensive research, disease heterogeneity and relapse remain a big challenge in MM therapeutics. We tried to dissect...
19.
Sun R, Zhang Z, Bao R, Guo X, Gu Y, Yang W, et al.
J Hepatol . 2022 Mar; 77(2):453-466. PMID: 35292350
Background & Aims: The liver is a metabolically active organ and is also 'tolerogenic', exhibiting sophisticated mechanisms of immune regulation that prevent pathogen attacks and tumorigenesis. How metabolism impacts the...
20.
Chen L, Morcelle C, Cheng Z, Chen X, Xu Y, Gao Y, et al.
Nat Cell Biol . 2022 Mar; 24(3):353-363. PMID: 35256775
As one of the most induced genes in activated macrophages, immune-responsive gene 1 (IRG1) encodes a mitochondrial metabolic enzyme catalysing the production of itaconic acid (ITA). Although ITA has an...