Maochun Qin
Overview
Explore the profile of Maochun Qin including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
532
Followers
0
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Recent Articles
1.
Dy G, Nesline M, Papanicolau-Sengos A, DePietro P, LeVea C, Early A, et al.
BMC Med Inform Decis Mak
. 2019 Jan;
19(1):14.
PMID: 30658646
Background: Regulatory approval of next generation sequencing (NGS) by the FDA is advancing the use of genomic-based precision medicine for the therapeutic management of cancer as standard care. Recent FDA...
2.
Chattopadhyay I, Wang J, Qin M, Gao L, Holtz R, Vessella R, et al.
Oncotarget
. 2017 Jan;
8(6):10324-10347.
PMID: 28055971
Progression of prostate cancer (PC) to castration-recurrent growth (CRPC) remains dependent on sustained expression and transcriptional activity of the androgen receptor (AR). A major mechanism contributing to CRPC progression is...
3.
Pruitt S, Qin M, Wang J, Kunnev D, Freeland A
PLoS Genet
. 2017 Jan;
13(1):e1006547.
PMID: 28045896
Insufficient licensing of DNA replication origins has been shown to result in genome instability, stem cell deficiency, and cancers. However, it is unclear whether the DNA damage resulting from deficient...
4.
Paluch B, Glenn S, Conroy J, Papanicolau-Sengos A, Bshara W, Omilian A, et al.
Oncotarget
. 2016 Dec;
8(2):3197-3205.
PMID: 27911273
Current criteria for identifying cancer patients suitable for immunotherapy with immune checkpoint blockers (ICBs) are subjective and prone to misinterpretation, as they mainly rely on the visual assessment of CD274...
5.
Wei L, Papanicolau-Sengos A, Liu S, Wang J, Conroy J, Glenn S, et al.
BMC Med Genomics
. 2016 Oct;
9(1):64.
PMID: 27756300
Background: The rapid adoption of next-generation sequencing provides an efficient system for detecting somatic alterations in neoplasms. The detection of such alterations requires a matched non-neoplastic sample for adequate filtering...
6.
Wei L, Liu S, Conroy J, Wang J, Papanicolau-Sengos A, Glenn S, et al.
Cold Spring Harb Mol Case Stud
. 2016 May;
1(1):a000380.
PMID: 27148567
Granular cell tumors are an uncommon soft tissue neoplasm. Malignant granular cell tumors comprise <2% of all granular cell tumors, are associated with aggressive behavior and poor clinical outcome, and...
7.
Kunnev D, Freeland A, Qin M, Wang J, Pruitt S
J Biol Methods
. 2016 Mar;
2(4).
PMID: 26949711
Nascent strand capture and release (NSCR) is a method for isolation of short nascent strands to identify origins of DNA replication. The protocol provided involves isolation of total DNA, denaturation,...
8.
Ma L, Qin M, Liu B, Hu Q, Wei L, Wang J, et al.
BMC Bioinformatics
. 2015 Oct;
16:331.
PMID: 26472134
Background: One of the most important somatic aberrations, copy number variations (CNVs) in tumor genomes is believed to have a high probability of harboring oncotargets. Detection of somatic CNVs is...
9.
Qin M, Liu B, Conroy J, Morrison C, Hu Q, Cheng Y, et al.
BMC Bioinformatics
. 2015 Apr;
16:66.
PMID: 25886838
Background: Somatically acquired structure variations (SVs) and copy number variations (CNVs) can induce genetic changes that are directly related to tumor genesis. Somatic SV/CNV detection using next-generation sequencing (NGS) data...
10.
Liu B, Conroy J, Morrison C, Odunsi A, Qin M, Wei L, et al.
Oncotarget
. 2015 Apr;
6(8):5477-89.
PMID: 25849937
Somatic Structural Variations (SVs) are a complex collection of chromosomal mutations that could directly contribute to carcinogenesis. Next Generation Sequencing (NGS) technology has emerged as the primary means of interrogating...