Manuela DEletto
Overview
Explore the profile of Manuela DEletto including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
542
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Recent Articles
1.
Muccioli S, Brillo V, Varanita T, Rossin F, Zaltron E, Velle A, et al.
Cell Death Dis
. 2023 Oct;
14(10):704.
PMID: 37898636
Skin cutaneous melanoma (SKCM) is the deadliest form of skin cancer due to its high heterogeneity that drives tumor aggressiveness. Melanoma plasticity consists of two distinct phenotypic states that co-exist...
2.
Occhigrossi L, Rossin F, Villella V, Esposito S, Abbate C, DEletto M, et al.
Front Immunol
. 2023 Mar;
14:1093212.
PMID: 36923406
Cystic fibrosis (CF) is a rare autosomal recessive disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The most common mutation is F508del-CFTR (ΔF) which leads...
3.
Gagliardi M, Saverio V, Rossin F, DEletto M, Corazzari M
Cell Death Discov
. 2023 Mar;
9(1):88.
PMID: 36894531
No abstract available.
4.
Rossin F, Ciccosanti F, DEletto M, Occhigrossi L, Fimia G, Piacentini M
Cell Mol Life Sci
. 2023 Jan;
80(2):52.
PMID: 36695883
One of the major mysteries in science is how it is possible to pack the cellular chromatin with a total length of over 1 m, into a small sphere with...
5.
Palucci I, Salustri A, De Maio F, Pereyra Boza M, Paglione F, Sali M, et al.
Int J Mol Sci
. 2023 Jan;
24(2).
PMID: 36674717
Host-directed therapies are emerging as a promising tool in the curing of difficult-to-treat infections, such as those caused by drug-resistant bacteria. In this study, we aim to test the potential...
6.
Occhigrossi L, DEletto M, Vecchio A, Piacentini M, Rossin F
Cell Death Discov
. 2022 Dec;
8(1):498.
PMID: 36572679
cGAS/STING axis is the major executor of cytosolic dsDNA sensing that leads to the production of type I interferon (IFNI) not only upon bacterial infection, but also in cancer cells,...
7.
Alonzi T, Aiello A, Petrone L, Fard S, DEletto M, Falasca L, et al.
Cells
. 2022 Jan;
11(1).
PMID: 35011614
The ongoing pandemic of coronavirus disease-2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), needs better treatment options both at antiviral and anti-inflammatory levels. It has been demonstrated...
8.
Erustes A, DEletto M, Guarache G, Ureshino R, Bincoletto C, da Silva Pereira G, et al.
J Neurosci Res
. 2021 Sep;
99(11):2932-2947.
PMID: 34510532
Mitochondria-associated ER membranes (MAMs) are formed by close and specific components in the contact sites between the endoplasmic reticulum (ER) and mitochondria, which participate in several cell functions, including lipid...
9.
Occhigrossi L, DEletto M, Barlev N, Rossin F
Int J Mol Sci
. 2021 Jul;
22(12).
PMID: 34198675
The cellular environment needs to be strongly regulated and the maintenance of protein homeostasis is crucial for cell function and survival. HSF1 is the main regulator of the heat shock...
10.
Occhigrossi L, Rossin F, DEletto M, Farrace M, Ciccosanti F, Petrone L, et al.
J Immunol
. 2021 May;
206(10):2420-2429.
PMID: 33941660
We have recently shown that type 2 transglutaminase (TG2) plays a key role in the host's inflammatory response during bacterial infections. In this study, we investigated whether the enzyme is...