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Manuel Velasco

Explore the profile of Manuel Velasco including associated specialties, affiliations and a list of published articles. Areas
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Articles 60
Citations 413
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Recent Articles
1.
Jimenez-Rodriguez A, Alvarado-Sanchez C, Velasco M, Lopez-Oliva E, Romero-Ceronio N, Ortiz-Andrade R, et al.
Chem Biodivers . 2025 Jan; :e202403028. PMID: 39890588
We aimed to determine the relaxant pathway of seventeen synthetic compounds derived from coumarin-3-carboxamide. An isolated rat aorta assay was used. To determine the vasorelaxant mode of action, receptor blockers...
2.
Velasco M, Romero-Ceronio N, Torralba R, Hernandez Abreu O, Vilchis-Reyes M, Alarcon-Matus E, et al.
Molecules . 2022 Jul; 27(14). PMID: 35889530
A simple and efficient one-pot, three-component synthetic method for the preparation of coumarin-3-carboxamides was carried out by the reaction of salicylaldehyde, aliphatic primary/secondary amines, and diethylmalonate. The protocol employs piperidine-iodine...
3.
Bermudez V, Rojas J, Salazar J, Martinez M, Olivar L, Calvo M, et al.
F1000Res . 2022 Feb; 7:230. PMID: 35136588
In 1980, Reuben Andresen observed that in certain individuals, obesity did not increase mortality, introducing an atypical phenotype called "healthy obese". Other studies reported that 10-15 % of lean individuals...
4.
Bermudez V, Salazar J, Fuenmayor J, Nava M, Ortega A, Duran P, et al.
J Obes . 2021 Jul; 2021:5514901. PMID: 34194826
Background: Visceral adiposity is related to insulin resistance (IR), a metabolic state considered as a risk factor for other cardiometabolic diseases. In that matter, mathematical indexes such as the visceral...
5.
Torres W, Chavez-Castillo M, Perez-Vicuna J, Carrasquero R, Diaz M, Gomez Y, et al.
Curr Pharm Des . 2021 May; 27(44):4434-4451. PMID: 34036919
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that involves a pathological inflammatory response against articular cartilage in multiple joints throughout the body. It is a complex disorder associated...
6.
Atencio A, de Manzo F, Velasco M
Curr Pharm Des . 2020 Aug; 26(35):4486-4495. PMID: 32787755
This article is an educational review about the fundamental aspects related to the proposal of the existence of a peripheral sympathetic reflex regulated by histamine, through its effect on presynaptic...
7.
Rivera R, Velasco M, Vidal D, Carrascosa J, Dauden E, Vilarrasa E, et al.
Dermatol Ther . 2020 Jul; 33(6):e14066. PMID: 32713119
The objective of the study was to evaluate efficacy and safety of ixekizumab in psoriasis patients under clinical practice conditions. Observational, retrospective, multicentre study that included patients with ixekizumab from...
8.
Torres W, Nava M, Galban N, Gomez Y, Morillo V, Rojas M, et al.
Curr Pharm Des . 2020 Jul; 26(35):4496-4508. PMID: 32674728
Aging is a time-dependent inevitable process, in which cellular homeostasis is affected, which has an impact on tissue function. This represents a risk factor for the development of numerous non-transmissible...
9.
Salazar J, Cano C, Perez J, Castro A, Diaz M, Garrido B, et al.
Curr Pharm Des . 2020 Jul; 26(35):4444-4460. PMID: 32611294
Lifestyle modifications such as energy restriction and increased physical activity are highly effective in the management of obesity. However, adherence to these therapeutic approaches is poor. On the other hand,...
10.
Chavez-Castillo M, Nunez V, Rojas M, Ortega A, Duran P, Pirela D, et al.
Curr Pharm Des . 2020 Jul; 26(35):4430-4443. PMID: 32611293
At present, the pathologic spectrum of obesity-insulin resistance (IR)-diabetes mellitus (DM) represents not only a pressing matter in public health but also a paramount object of study in biomedical research,...