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Manu Shivakumar

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Articles 36
Citations 367
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Recent Articles
11.
Bae J, Jung Y, Lee J, Shivakumar M, Park C, Park J, et al.
Fertil Steril . 2023 Nov; 120(6):1227-1233. PMID: 38008468
Objective: To evaluate the risk of metabolic syndrome (MS) after recurrent pregnancy loss (RPL) using UK Biobank data. A history of pregnancy loss is associated with the development of cardiovascular...
12.
Lee S, Shivakumar M, Xiao B, Jung S, Nam Y, Yun J, et al.
Am J Obstet Gynecol . 2023 Mar; 229(3):298.e1-298.e19. PMID: 36933686
Background: Hypertensive disorders during pregnancy are associated with the risk of long-term cardiovascular disease after pregnancy, but it has not yet been determined whether genetic predisposition for hypertensive disorders during...
13.
Lee S, Shivakumar M, Park J, Jung Y, Choe E, Kwak S, et al.
Cardiovasc Diabetol . 2022 Oct; 21(1):221. PMID: 36309714
Background: Previous studies showed that gestational diabetes mellitus (GDM) can be a risk factor for subsequent atherosclerotic cardiovascular disease. However, there is a paucity of information regarding diverse cardiovascular outcomes...
14.
Yun J, Jung S, Shivakumar M, Xiao B, Khera A, Park W, et al.
Front Cardiovasc Med . 2022 Sep; 9:919374. PMID: 36061534
Background: Previous studies primarily targeted the ability of polygenic risk scores (PRSs) to predict a specific disease, and only a few studies have investigated the association between genetic risk scores...
15.
Yun J, Jung S, Shivakumar M, Xiao B, Khera A, Won H, et al.
Cardiovasc Diabetol . 2022 Jul; 21(1):131. PMID: 35836215
Background: Few studies have examined associations between genetic risk for type 2 diabetes (T2D), lifestyle, clinical risk factors, and cardiovascular disease (CVD). We aimed to investigate the association of and...
16.
Choe E, Shivakumar M, Lee S, Verma A, Kim D
Int J Obes (Lond) . 2022 Jun; 46(9):1686-1693. PMID: 35752651
Background: Obesity is a global pandemic disease whose prevalence is increasing worldwide. The clinical relevance of a polygenic risk score (PRS) for obesity has not been fully elucidated in Asian...
17.
Jung S, Hao J, Shivakumar M, Nam Y, Kim J, Kim M, et al.
Br J Cancer . 2022 Mar; 126(11):1539-1547. PMID: 35249104
Background: Systemic inflammation is associated with survival outcomes in colon cancer. However, it is not well-known which systemic inflammatory marker is a powerful prognostic marker in patients with colon cancer....
18.
Sriram V, Shivakumar M, Jung S, Nam Y, Bang L, Verma A, et al.
Gigascience . 2022 Feb; 11. PMID: 35166337
Background: Disease complications, the onset of secondary phenotypes given a primary condition, can exacerbate the long-term severity of outcomes. However, the exact cause of many of these cross-phenotype associations is...
19.
Choe E, Shivakumar M, Verma A, Verma S, Choi S, Kim J, et al.
Sci Rep . 2022 Feb; 12(1):1930. PMID: 35121771
The expanding use of the phenome-wide association study (PheWAS) faces challenges in the context of using International Classification of Diseases billing codes for phenotype definition, imbalanced study population ethnicity, and...
20.
Sriram V, Nam Y, Shivakumar M, Verma A, Jung S, Lee S, et al.
J Pers Med . 2021 Dec; 11(12). PMID: 34945853
Background: Recent studies have found that women with obstetric disorders are at increased risk for a variety of long-term complications. However, the underlying pathophysiology of these connections remains undetermined. A...