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Manqi Chen

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Articles 10
Citations 95
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Recent Articles
1.
Sun C, Guo R, Ye X, Tang S, Chen M, Zhou P, et al.
iScience . 2024 May; 27(5):109748. PMID: 38706838
We previously reported that loss of function of TYW1 led to cerebral palsy with severe intellectual disability through reduced neural proliferation. However, whether TYW1 loss affects neural differentiation is unknown....
2.
Kong X, Li R, Chen M, Zheng R, Wang J, Sun C, et al.
Proc Natl Acad Sci U S A . 2024 Mar; 121(12):e2318176121. PMID: 38483994
Endogenous retroviruses (ERVs) are frequently reactivated in mammalian placenta. It has been proposed that ERVs contribute to shaping the gene regulatory network of mammalian trophoblasts, dominantly acting as species- and...
3.
Cao G, Guo R, Chen M, Sun C, Wang J
J Cell Physiol . 2023 Jun; 238(7):1580-1591. PMID: 37305966
Poly(ADP-ribosyl)ation (PARylation) is an important post-translational modification of proteins that involves the transfer of ADP-ribose moieties, and plays important roles in many biological processes including DNA repair, gene expression, RNA...
4.
Cai J, Ji Z, Wu J, Chen L, Zheng D, Chen Y, et al.
Front Genet . 2022 Sep; 13:949314. PMID: 36092873
Breast cancer (BC), the most common malignancy in women, has a high cancer-related mortality. Endoplasmic reticulum stress (ERS), a response to the accumulation of unfolded proteins, has emerging roles in...
5.
Yu H, Chen M, Hu Y, Ou S, Yu X, Liang S, et al.
Cell Stem Cell . 2022 Jul; 29(7):1031-1050.e12. PMID: 35803225
Reprogramming of H3K9me3-dependent heterochromatin is required for early development. How H3K9me3 is involved in early human development remains, however, largely unclear. Here, we resolve the temporal landscape of H3K9me3 during...
6.
Yu X, Liang S, Chen M, Yu H, Li R, Qu Y, et al.
Cell Rep . 2022 Jun; 39(12):110994. PMID: 35732112
In human embryos, major zygotic genome activation (ZGA) initiates at the eight-cell (8C) stage. Abnormal ZGA leads to developmental defects and even contributes to the failure of human blastocyst formation...
7.
Bai S, Huang B, Fu S, Zhu M, Hu L, Zhu L, et al.
Front Immunol . 2021 Mar; 12:641281. PMID: 33763083
Female Genital Tract (FGT) is an important micro-ecological area of human body. Microbiota in the lower reproductive tract may subsequently invade the uterine cavity during embryo implantation and produce immune...
8.
Fang T, Chen M, Yu W, Ma T, Su Z, Chan D, et al.
J Gynecol Obstet Hum Reprod . 2021 Jan; 50(8):102072. PMID: 33508484
Objectives: To evaluate the predictive value of endometrial thickness (EMT) during in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) cycles for ectopic pregnancy (EP). Methods: A total of 3068 patients with...
9.
Ou Y, Zhu L, Wei X, Bai S, Chen M, Chen H, et al.
Cell Death Dis . 2020 Jun; 11(6):479. PMID: 32587240
Mounting evidence has revealed that impaired spiral artery remodeling, placental dysfunction, and inadequate trophoblast invasion are closely correlated with the etiology and pathogenesis of pre-eclampsia (PE). Moreover, defective trophoblast invasion...
10.
Ou Y, Liu M, Zhu L, Deng K, Chen M, Chen H, et al.
Taiwan J Obstet Gynecol . 2019 Nov; 58(6):769-777. PMID: 31759525
Objective: To determine the expression profiles of circular RNAs (circRNAs) of women with severe pre-eclampsia (sPE group) versus normal pregnancies (normal control group). Materials And Methods: RNA-sequencing (RNA-seq) was conducted...