Manon Ruffin
Overview
Explore the profile of Manon Ruffin including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
419
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Recent Articles
11.
Bigot J, Guillot L, Guitard J, Ruffin M, Corvol H, Balloy V, et al.
Front Immunol
. 2020 Jun;
11:1041.
PMID: 32528481
is an environmental filamentous fungus that can be pathogenic for humans, wherein it is responsible for a large variety of clinical forms ranging from allergic diseases to life-threatening disseminated infections....
12.
Ruffin M, Mercier J, Calmel C, Mesinele J, Bigot J, Sutanto E, et al.
Cell Mol Life Sci
. 2020 Mar;
77(17):3311-3323.
PMID: 32166393
The solute carrier family 6 member 14 (SLC6A14) protein imports and concentrates all neutral amino acids as well as the two cationic acids lysine and arginine into the cytoplasm of...
13.
Ruffin M, Thompson K, Corvol H, Guillot L
BMC Res Notes
. 2020 Jan;
12(1):804.
PMID: 31900205
Objectives: Family with sequence similarity 13 member A (FAM13A) genetic variants have been associated with several chronic respiratory diseases including chronic obstructive pulmonary disease (COPD), cystic fibrosis (CF), idiopathic pulmonary...
14.
Paranjapye A, Ruffin M, Harris A, Corvol H
J Cyst Fibros
. 2019 Nov;
19 Suppl 1:S10-S14.
PMID: 31734115
In patients with cystic fibrosis (CF), genetic variants within and outside the CFTR locus contribute to the variability of the disease severity. CFTR transcription is tightly regulated by cis-regulatory elements...
15.
Bigot J, Guillot L, Guitard J, Ruffin M, Corvol H, Chignard M, et al.
J Infect Dis
. 2019 Nov;
221(6):1000-1005.
PMID: 31678998
Human bronchial epithelial cells play a key role in airway immune homeostasis. We hypothesized that these sentinel cells can remember a previous contact with pathogen compounds and respond nonspecifically to...
16.
Repair Process Impairment by in Epithelial Tissues: Major Features and Potential Therapeutic Avenues
Ruffin M, Brochiero E
Front Cell Infect Microbiol
. 2019 Jun;
9:182.
PMID: 31214514
Epithelial tissues protecting organs from the environment are the first-line of defense against pathogens. Therefore, efficient repair mechanisms after injury are crucial to maintain epithelial integrity. However, these healing processes...
17.
Valera F, Ruffin M, Adam D, Maille E, Ibrahim B, Berube J, et al.
J Allergy Clin Immunol
. 2018 Jun;
143(2):591-603.e3.
PMID: 29935218
Background: The effect of Staphylococcus aureus on nasal epithelial repair has never been assessed in patients with chronic rhinosinusitis with nasal polyps (CRSwNP). Objective: This study aimed to determine whether...
18.
Adam D, Bilodeau C, Sognigbe L, Maille E, Ruffin M, Brochiero E
J Cyst Fibros
. 2018 Apr;
17(6):705-714.
PMID: 29661510
Background: Progressive airway damage due to bacterial infections, especially with Pseudomonas aeruginosa remains the first cause of morbidity and mortality in CF patients. Our previous work revealed a repair delay...
19.
Ruffin M, Roussel L, Maille E, Rousseau S, Brochiero E
Am J Physiol Lung Cell Mol Physiol
. 2018 Jan;
314(4):L635-L641.
PMID: 29351441
Cystic fibrosis patients exhibit chronic Pseudomonas aeruginosa respiratory infections and sustained proinflammatory state favoring lung tissue damage and remodeling, ultimately leading to respiratory failure. Loss of cystic fibrosis transmembrane conductance...
20.
Maille E, Ruffin M, Adam D, Messaoud H, LaFayette S, McKay G, et al.
Front Cell Infect Microbiol
. 2017 Nov;
7:470.
PMID: 29177135
The function of cystic fibrosis transmembrane conductance regulator (CFTR) channels is crucial in human airways. However unfortunately, chronic infection has been shown to impair CFTR proteins in non-CF airway epithelial...