Manoj Kumar K Azhagiri
Overview
Explore the profile of Manoj Kumar K Azhagiri including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
26
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0
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Recent Articles
1.
Chandraprabha P, Azhagiri M, Venkatesan V, Magis W, Prasad K, Suresh S, et al.
Stem Cell Res Ther
. 2024 Dec;
15(1):504.
PMID: 39736768
Background: Sickle cell disease (SCD) and β-thalassemia patients with elevated gamma globin (HBG1/G2) levels exhibit mild or no symptoms. To recapitulate this natural phenomenon, the most coveted gene therapy approach...
2.
Venkatesan V, Christopher A, Rhiel M, Azhagiri M, Babu P, Walavalkar K, et al.
Mol Ther Nucleic Acids
. 2023 May;
32:671-688.
PMID: 37215154
Reactivation of fetal hemoglobin (HbF) is a commonly adapted strategy to ameliorate β-hemoglobinopathies. However, the continued production of defective adult hemoglobin (HbA) limits HbF tetramer production affecting the therapeutic benefits....
3.
Azhagiri M, Babu P, Venkatesan V, Thangavel S
Stem Cell Res Ther
. 2021 Sep;
12(1):500.
PMID: 34503562
The advent of next-generation genome engineering tools like CRISPR-Cas9 has transformed the field of gene therapy, rendering targeted treatment for several incurable diseases. Hematopoietic stem and progenitor cells (HSPCs) continue...
4.
Christopher A, Venkatesan V, Karuppusamy K, Srinivasan S, Babu P, Azhagiri M, et al.
Hum Gene Ther
. 2021 Sep;
33(3-4):188-201.
PMID: 34486377
CD34CD133CD90 hematopoietic stem cells (HSCs) are responsible for long-term multilineage hematopoiesis, and the high frequency of gene-modified HSCs is crucial for the success of hematopoietic stem and progenitor cell (HSPC)...