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Manmohan Kumar

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Articles 18
Citations 112
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Recent Articles
1.
Kumar M, Sharma S, Kumar J, Barik S, Mazumder S
Curr Res Immunol . 2024 Apr; 5:100077. PMID: 38572399
Macrophages restrain microbial infection and reinstate tissue homeostasis. The mitochondria govern macrophage metabolism and serve as pivot in innate immunity, thus acting as immunometabolic regulon. Metabolic pathways produce electron flows...
2.
Sharma S, Kumar M, Kumar J, Mazumder S
Cells . 2023 Jun; 12(11). PMID: 37296630
Canonical Wnt signaling plays a major role in regulating microbial pathogenesis. However, to date, its involvement in infection is not well known. Using zebrafish () kidney macrophages (ZKM), we report...
3.
Kumar M, Sharma S, Mazumder S
Front Cell Infect Microbiol . 2023 Jun; 13:1135203. PMID: 37260703
The immune system of a host contains a group of heterogeneous cells with the prime aim of restraining pathogenic infection and maintaining homeostasis. Recent reports have proved that the various...
4.
Kumar M, Sharma S, Haque M, Kumar J, Hathi U, Mazumder S
Front Immunol . 2022 Jul; 13:931021. PMID: 35860264
Toll-like receptors (TLRs) are epitomized as the first line of defense against pathogens. Amongst TLRs, TLR22 is expressed in non-mammalian aquatic vertebrates, including fish. Using headkidney macrophages (HKM) of ,...
5.
Kumar J, Kumar M, Sharma S, Srivastava N, Singh R, Hussain M, et al.
Fish Shellfish Immunol . 2022 Jun; 127:357-365. PMID: 35772676
Aeromonas hydrophila is an important aquatic zoonotic pathogen that causes septicemia, necrotizing fasciitis and gastroenteritis in various aquatic and non-aquatic animals. However, the pathogenesis of A. hydrophila is not fully...
6.
Kumar M, Shelly A, Dahiya P, Ray A, Mazumder S
Virulence . 2021 Dec; 13(1):60-76. PMID: 34967692
The molecular mechanisms underlying -pathogenesis are not well understood. Using head kidney macrophages (HKM) of , we previously reported the role of ER-stress in -induced pathogenesis. Here, we report that...
7.
Kumar M, Kumar J, Sharma S, Hussain M, Shelly A, Das B, et al.
Mol Immunol . 2021 Jul; 137:114-123. PMID: 34242920
Toll-like receptors (TLRs) represent first line of host defence against microbes. Amongst different TLRs, TLR22 is exclusively expressed in non-mammalian vertebrates, including fish. The precise role of TLR22 in fish-immunity...
8.
Sharma S, Kumar M, Kumar J, Srivastava N, Hussain M, Shelly A, et al.
Dev Comp Immunol . 2021 May; 122:104111. PMID: 33933535
Molecular underpinning of mycobacteria-induced CNS-pathology is not well understood. In the present study, zebrafish were infected with Mycobacterium fortuitum and the prognosis of CNS-pathogenesis studied. We observed M. fortuitum triggers...
9.
Hussain M, Datta D, Singh R, Kumar M, Kumar J, Mazumder S
Sci Rep . 2019 Aug; 9(1):12330. PMID: 31444398
The implications of TLR-2 mediated alterations in cytosolic-Ca((Ca)) levels in M. smegmatis infections is not well known. Using headkidney macrophages (HKM) from Clarias gariepinus, we observed TLR-2 signalling is required...
10.
Majumdar T, Sharma S, Kumar M, Hussain M, Chauhan N, Kalia I, et al.
Cell Death Dis . 2019 Feb; 10(3):161. PMID: 30770800
Recent studies have documented the diverse role of host immunity in infection by the protozoan parasite, Toxoplasma gondii. However, the contribution of the β-catenin pathway in this process has not...