Manjunatha R Benakanakere
Overview
Explore the profile of Manjunatha R Benakanakere including associated specialties, affiliations and a list of published articles.
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23
Citations
618
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Recent Articles
1.
Nuth M, Benakanakere M, Ricciardi R
Int J Oncol
. 2022 Feb;
60(4).
PMID: 35211767
Squamous cell carcinoma is the major form of malignancy that arises in head and neck cancer. The modest improvement in the 5‑year survival rate underpins its complex etiology and provides...
2.
Tanaka U, Kajioka S, Finoti L, Palioto D, Kinane D, Benakanakere M
Biomedicines
. 2021 Mar;
9(2).
PMID: 33671221
DNA methylation controls several inflammatory genes affecting bone homeostasis. Hitherto, inhibition of DNA methylation in vivo in the context of periodontitis and osteoclastogenesis has not been attempted. Ligature-induced periodontitis in...
3.
Teixeira H, Zhao J, Kazmierski E, Kinane D, Benakanakere M
Cells
. 2020 Aug;
9(8).
PMID: 32824595
The role of the adaptor molecule MyD88 is thought to be independent of Toll-like receptor 3 (TLR3) signaling. In this report, we demonstrate a previously unknown role of MyD88 in...
4.
Ando-Suguimoto E, Benakanakere M, Mayer M, Kinane D
Pathogens
. 2020 Apr;
9(4).
PMID: 32230992
In aggressive periodontitis, the dysbiotic microbial community in the subgingival crevice, which is abundant in Aggregatibacter actinomycetemcomitans, interacts with extra- and intracellular receptors of host cells, leading to exacerbated inflammation...
5.
Teixeira H, Zhao J, Kinane D, Benakanakere M
Mol Immunol
. 2019 Apr;
111:27-31.
PMID: 30954023
The oral cavity is home for a plethora of bacteria and viruses. Epithelial barriers encounter these micro-organisms and recognize them via pathogen recognition receptors (PRRs) that instigate antibacterial and antiviral...
6.
Alyami H, Finoti L, Teixeira H, Aljefri A, Kinane D, Benakanakere M
Microb Pathog
. 2019 Apr;
131:53-64.
PMID: 30940608
Polymorphonuclear neutrophils (PMNs) are indispensable in fighting infectious microbes by adopting various antimicrobial strategies including phagocytosis and neutrophil extracellular traps (NETs). Although the role and importance of PMNs in periodontal...
7.
Benakanakere M, Finoti L, Tanaka U, Grant G, Scarel-Caminaga R, Kinane D
Sci Rep
. 2016 Aug;
6:31180.
PMID: 27499075
Interleukin-8 (IL-8) gene polymorphisms have been considered as susceptibility factors in periodontal disease. However, the functional roles of IL-8 gene haplotypes have not been investigated. Here, we demonstrate for the...
8.
Abe T, AlSarhan M, Benakanakere M, Maekawa T, Kinane D, Cancro M, et al.
J Immunol
. 2015 Jul;
195(4):1427-35.
PMID: 26150532
B-lineage cells (B lymphocytes and plasma cells) predominate in the inflammatory infiltrate of human chronic periodontitis. However, their role in disease pathogenesis and the factors responsible for their persistence in...
9.
Li S, Dong G, Moschidis A, Ortiz J, Benakanakere M, Kinane D, et al.
PLoS One
. 2013 Nov;
8(11):e78541.
PMID: 24265696
P. gingivalis is a prominent periodontal pathogen that has potent effects on host cells. In this study we challenged gingival epithelial cells with P. gingivalis with the aim of assessing...
10.
Kinane J, Benakanakere M, Zhao J, Hosur K, Kinane D
Cell Microbiol
. 2012 Mar;
14(7):1085-96.
PMID: 22381126
Porphyromonas gingivalis, a Gram-negative oral pathogen, has been shown to induce apoptosis in human gingival epithelial cells, yet the underlining cellular mechanisms controlling this process are poorly understood. We have...