Manja Wobus
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Explore the profile of Manja Wobus including associated specialties, affiliations and a list of published articles.
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60
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1109
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Recent Articles
1.
Dennison N, Fusenig M, Gronnert L, Maitz M, Ramirez Martinez M, Wobus M, et al.
Adv Healthc Mater
. 2024 Mar;
13(18):e2400388.
PMID: 38465502
Hydrogel-based 3D cell cultures can recapitulate (patho)physiological phenomena ex vivo. However, due to their complex multifactorial regulation, adapting these tissue and disease models for high-throughput screening workflows remains challenging. In...
2.
Ibneeva L, Singh S, Sinha A, Eski S, Wehner R, Rupp L, et al.
PLoS Biol
. 2024 Feb;
22(2):e3002517.
PMID: 38422172
A subpopulation of deeply quiescent, so-called dormant hematopoietic stem cells (dHSCs) resides at the top of the hematopoietic hierarchy and serves as a reserve pool for HSCs. The state of...
3.
Towers R, Trombello L, Fusenig M, Tunger A, Baumann A, Savoldelli R, et al.
Cancer Immunol Immunother
. 2024 Jan;
73(1):8.
PMID: 38231344
Bone marrow mesenchymal stromal cells (MSCs) have been described as potent regulators of T-cell function, though whether they could impede the effectiveness of immunotherapy against acute myeloid leukemia (AML) is...
4.
Kovtun I, von Bonin M, Ibneeva L, Frimmel J, Middeke J, Kunadt D, et al.
Leukemia
. 2023 Dec;
38(2):393-397.
PMID: 38066329
No abstract available.
5.
6.
Zimmermann R, Nitschke M, Magno V, Freudenberg U, Sockel K, Stolzel F, et al.
Small Methods
. 2023 Mar;
7(6):e2201157.
PMID: 36978251
Identifying characteristic extracellular matrix (ECM) variants is a key challenge in mechanistic biology, bioengineering, and medical diagnostics. The reported study demonstrates the potential of time-of-flight secondary ion mass spectrometry (ToF-SIMS)...
7.
Deniz I, Karbanova J, Wobus M, Bornhauser M, Wimberger P, Kuhlmann J, et al.
Cell Commun Signal
. 2023 Feb;
21(1):36.
PMID: 36788616
Background: Multipotent mesenchymal stromal cells (MSCs) are precursors of various cell types. Through soluble factors, direct cell-cell interactions and other intercellular communication mechanisms such as extracellular vesicles and tunneling nanotubes,...
8.
Stolzel F, Fordham S, Nandana D, Lin W, Blair H, Elstob C, et al.
JCI Insight
. 2022 Dec;
8(2).
PMID: 36480300
Precision medicine can significantly improve outcomes for patients with cancer, but implementation requires comprehensive characterization of tumor cells to identify therapeutically exploitable vulnerabilities. Here, we describe somatic biallelic TET2 mutations...
9.
Kruger T, Wehner R, Herbig M, Krater M, Kramer M, Middeke J, et al.
Front Immunol
. 2022 Oct;
13:1005554.
PMID: 36311725
Functional impairment of the bone marrow (BM) niche has been suggested as a major reason for prolonged cytopenia and secondary graft failure after allogeneic hematopoietic cell transplantation (alloHCT). Because mesenchymal...
10.
Luspatercept mitigates bone loss driven by myelodysplastic neoplasms and estrogen-deficiency in mice
Weidner H, Wobus M, Hofbauer L, Rauner M, Platzbecker U
Leukemia
. 2022 Sep;
36(11):2715-2718.
PMID: 36175549
No abstract available.