Manisha V Ghate
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Explore the profile of Manisha V Ghate including associated specialties, affiliations and a list of published articles.
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19
Citations
150
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Recent Articles
1.
Dhande J, Saikia K, Singh D, Bagul R, Kulkarni S, Ghate M, et al.
AIDS
. 2020 Aug;
34(11):1603-1608.
PMID: 32769762
Objective: The HIV-1-specific antibodies are being considered for prevention and therapy in HIV infection. For effective antibody response, presence of functionally competent memory B cells (MEBs) is important; however, HIV-infection...
2.
Singh H, Samani D, Nema V, Ghate M, Gangakhedkar R
Mediators Inflamm
. 2018 Jun;
2018:4398150.
PMID: 29849489
The severity of hepatic injury depends upon cytokines. Previous studies associated allele 2 with production. Hence, we examined the association of and polymorphisms with ARV-associated hepatotoxicity. Genotyping of (VNTR), (-511C/T)...
3.
Singh H, Samani D, Nambiar N, Ghate M, Gangakhedkar R
APMIS
. 2018 Mar;
126(4):329-336.
PMID: 29575199
Remodeling of extracellular matrix (ECM) by matrix metalloproteinases (MMPs) is a presumed reason for the development of HIV-associated neurocognitive disorders (HAND). The coding region polymorphism in MMP-21 572C/T gene may...
4.
Singh H, Marathe S, Nain S, Samani D, Nema V, Ghate M, et al.
J Biosci
. 2018 Jan;
42(3):481-490.
PMID: 29358561
The pathogenesis of HIV-associated neurocognitive disorder (HAND) is modulated by host genetic susceptibility factors such as Matrix metalloproteinases (MMPs). Promoter polymorphism of MMP-1 and MMP-3 may modify the expression of...
5.
Singh H, Samani D, Nambiar N, Ghate M, Gangakhedkar R
Gene
. 2018 Jan;
646:83-90.
PMID: 29292194
Matrix metalloproteinases (MMPs) are well-known as mediators of neuroinflammation in HIV-associated neurocognitive disorder (HAND). Increased levels of MMP-8 have been observed in the HIV-infected patients. Thus, the aim of this...
6.
Singh H, Samani D, Ghate M, Gangakhedkar R
J Gene Med
. 2017 Dec;
20(2-3):e3004.
PMID: 29282802
Background: TRIM5α and BST-2 are cellular restriction factors affecting the HIV-1 infection and its progression. Genetic variability in these genes alters the expression pattern. Hence, we aimed to examine the...
7.
Karade S, Kulkarni S, Ghate M, Patil A, Londhe R, Salvi S, et al.
PLoS One
. 2017 Aug;
12(8):e0181889.
PMID: 28763465
Background: The free antiretroviral therapy (ART) program in India still relies on the clinico-immunological monitoring for diagnosis of treatment failure. As the nucleoside reverse transcriptase inhibitor (NRTI) backbone is shared...
8.
Karade S, Ghate M, Chaturbhuj D, Kadam D, Shankar S, Gaikwad N, et al.
Medicine (Baltimore)
. 2016 Sep;
95(37):e4886.
PMID: 27631260
The free antiretroviral therapy (ART) program in India has scaled up to register second largest number of people living with HIV/AIDS across the globe. To assess the effectiveness of current...
9.
Ghate M, Kadam D, Gurav N, Rewari B, Gangakhedkar R
J Assoc Physicians India
. 2016 Sep;
63(10):94-5.
PMID: 27608708
No abstract available.
10.
Singh H, Marathe S, Nema V, Ghate M, Gangakhedkar R
J Gene Med
. 2016 Aug;
18(9):250-7.
PMID: 27551834
Background: Astrocytes are susceptible to HIV-1 infection. Neurocognitive dysfunction has also been associated with the toxicity of certain antiretroviral drugs. HIV-1 induced neurological toxicity has been associated with deficiency of...