Mani Ramaswami
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Explore the profile of Mani Ramaswami including associated specialties, affiliations and a list of published articles.
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74
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2401
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Recent Articles
1.
Roselli C, Ramaswami M, Aranha M
Bio Protoc
. 2024 Nov;
14(21):e5102.
PMID: 39525971
Long-lasting memories are a core aspect of an animal's life. Such memories are characterized by unique molecular mechanisms and often unique circuitry, neither of which are completely understood in vivo....
2.
Petrauskas A, Fortunati D, Kandi A, Pothapragada S, Agrawal K, Singh A, et al.
PLoS Genet
. 2024 May;
20(5):e1011251.
PMID: 38768217
Ataxin-2 (ATXN2) is a gene implicated in spinocerebellar ataxia type II (SCA2), amyotrophic lateral sclerosis (ALS) and Parkinsonism. The encoded protein is a therapeutic target for ALS and related conditions....
3.
Trisal S, VijayRaghavan K, Ramaswami M
Bio Protoc
. 2023 Dec;
13(23):e4891.
PMID: 38130897
Habituation, the process by which animals learn to ignore insignificant stimuli, facilitates engagement with salient features of the environment. However, neural mechanisms underlying habituation also allow responses to familiar stimuli...
4.
Aranha M, Ramaswami M
Curr Biol
. 2022 Sep;
32(18):R954-R957.
PMID: 36167044
Mammals and insects appear to have emotional states with features characteristic of human depression. A new study has defined a neural circuit including serotonergic neurons that drive sugar-induced relief from...
5.
Chen N, Zhang Y, Adel M, Kuklin E, Reed M, Mardovin J, et al.
Curr Biol
. 2022 May;
32(12):2730-2738.e5.
PMID: 35545085
How compartment-specific local proteomes are generated and maintained is inadequately understood, particularly in neurons, which display extreme asymmetries. Here we show that local enrichment of Ca/calmodulin-dependent protein kinase II (CaMKII)...
6.
Trisal S, Aranha M, Chodankar A, VijayRaghavan K, Ramaswami M
J Neurosci
. 2022 Mar;
42(14):2930-2941.
PMID: 35232763
Habituated animals retain a latent capacity for robust engagement with familiar stimuli. In most instances, the ability to override habituation is best explained by postulating that habituation arises from the...
7.
Singh A, Kandi A, Jayaprakashappa D, Thuery G, Purohit D, Huelsmeier J, et al.
Mol Biol Cell
. 2022 Jan;
33(3):ar25.
PMID: 34985933
Cells respond to stress with translational arrest, robust transcriptional changes, and transcription-independent formation of mRNP assemblies termed stress granules (SGs). Despite considerable interest in the role of SGs in oxidative,...
8.
Huelsmeier J, Walker E, Bakthavachalu B, Ramaswami M
G3 (Bethesda)
. 2021 Oct;
11(12).
PMID: 34718534
The Ataxin-2 (Atx2) protein contributes to the progression of neurodegenerative phenotypes in animal models of amyotrophic lateral sclerosis (ALS), type 2 spinocerebellar ataxia (SCA-2), Parkinson's disease, and Huntington's disease (HD)....
9.
Boto T, Ramaswami M
Curr Biol
. 2021 Aug;
31(16):R1009-R1011.
PMID: 34428410
Prior experience is known to deeply influence new learning. A recent study describes a neural mechanism where initial sensory experience promotes the establishment of a competing and/or cooperative memory trace...
10.
Roselli C, Ramaswami M, Boto T, Cervantes-Sandoval I
Front Behav Neurosci
. 2021 Apr;
15:662129.
PMID: 33859556
Understanding the nature of the molecular mechanisms underlying memory formation, consolidation, and forgetting are some of the fascinating questions in modern neuroscience. The encoding, stabilization and elimination of memories, rely...