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Manfred Zehender

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Articles 113
Citations 919
Followers 0
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Recent Articles
1.
Oettinger V, Zimmermann J, von Zur Muhlen C, Kaier K, Faber T, Paulus T, et al.
Clin Res Cardiol . 2024 Sep; PMID: 39285008
Background: A variety of health-related mobile applications (apps) and wearables often encompass a narrow application area. Our study therefore aims to provide the basis for the development of an app...
2.
Bains S, Giammarino L, Nimani S, Alerni N, Tester D, Kim C, et al.
Eur Heart J . 2024 Aug; 45(36):3751-3763. PMID: 39115049
Background And Aims: Type 1 long QT syndrome (LQT1) is caused by pathogenic variants in the KCNQ1-encoded Kv7.1 potassium channels, which pathologically prolong ventricular action potential duration (APD). Herein, the...
3.
Bodi I, Mettke L, Michaelides K, Hornyik T, Meier S, Nimani S, et al.
Cardiovasc Res . 2024 Jul; 120(13):1550-1561. PMID: 39018021
Aims: Short QT syndrome type 1 (SQT1) is a genetic channelopathy caused by gain-of-function variants in human-ether-a-go-go (HERG) underlying the rapid delayed-rectifier K+ current (IKr), leading to QT-shortening, ventricular arrhythmias,...
4.
Oettinger V, Hilgendorf I, Wolf D, Stachon P, Heidenreich A, Zehender M, et al.
J Cardiol . 2024 Feb; 84(2):99-104. PMID: 38307247
Background: In transcatheter aortic valve replacement (TAVR), complications may force the need for a surgical bailout, but knowledge is rare about outcomes in Germany. Methods: Using national health records, we...
5.
Oettinger V, Hehn P, Bode C, Zehender M, von Zur Muhlen C, Westermann D, et al.
J Interv Cardiol . 2023 Nov; 2023:3723657. PMID: 38028025
Aims: Literature on percutaneous coronary intervention (PCI) stated an inverse relationship between hospital volume and mortality, but the effects on other characteristics are unclear. Methods: Using German national records, all...
6.
Oettinger V, Hilgendorf I, Wolf D, Rilinger J, Maier A, Zehender M, et al.
Clin Res Cardiol . 2023 Nov; 113(1):168-176. PMID: 37982864
Background: Previously, overall comparable outcomes were seen for balloon-expandable (BE) or self-expanding (SE) transfemoral transcatheter aortic valve replacement (TAVR). However, subgroup analyses based on large case numbers are still needed....
7.
Oettinger V, Hilgendorf I, Wolf D, Stachon P, Heidenreich A, Zehender M, et al.
Front Cardiovasc Med . 2023 May; 10:1091983. PMID: 37200971
Background: In pure aortic regurgitation, transcatheter aortic valve replacement (TAVR) is not yet used on a regular base. Due to constant development of TAVR, it is necessary to analyze current...
8.
Giannetti F, Barbieri M, Shiti A, Casini S, Sager P, Das S, et al.
Europace . 2023 Apr; 25(5). PMID: 37099628
Aims: Current long QT syndrome (LQTS) therapy, largely based on beta-blockade, does not prevent arrhythmias in all patients; therefore, novel therapies are warranted. Pharmacological inhibition of the serum/glucocorticoid-regulated kinase 1...
9.
Lewetag R, Nimani S, Alerni N, Hornyik T, Jacobi S, Moss R, et al.
J Physiol . 2023 Apr; 602(18):4511-4527. PMID: 37082830
Electromechanical reciprocity - comprising electro-mechanical (EMC) and mechano-electric coupling (MEC) - provides cardiac adaptation to changing physiological demands. Understanding electromechanical reciprocity and its impact on function and heterogeneity in pathological...
10.
Heidenreich A, Stachon P, Oettinger V, Hilgendorf I, Heidt T, Rilinger J, et al.
BMC Cardiovasc Disord . 2023 Apr; 23(1):187. PMID: 37024779
Background: COVID-19 has caused the deferral of millions of elective procedures, likely resulting in a backlog of cases. We estimate the number of postponed surgical aortic valve replacement (sAVR) and...