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Mandana Zandian

Explore the profile of Mandana Zandian including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 759
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Recent Articles
1.
Mariscal J, Vagner T, Kim M, Zhou B, Chin A, Zandian M, et al.
J Extracell Vesicles . 2020 Sep; 9(1):1764192. PMID: 32944167
Extracellular vesicles (EVs) are membrane-enclosed particles that play an important role in cancer progression and have emerged as a promising source of circulating biomarkers. Protein -acylation, frequently called palmitoylation, has...
2.
Vagner T, Spinelli C, Minciacchi V, Balaj L, Zandian M, Conley A, et al.
J Extracell Vesicles . 2018 Aug; 7(1):1505403. PMID: 30108686
Cancer-derived extracellular vesicles (EVs) are membrane-enclosed structures of highly variable size. EVs contain a myriad of substances (proteins, lipid, RNA, DNA) that provide a reservoir of circulating molecules, thus offering...
3.
Lee D, Zandian M, Kuo J, Mott K, Chen S, Arditi M, et al.
PLoS Pathog . 2017 May; 13(5):e1006401. PMID: 28542613
We have established two mouse models of central nervous system (CNS) demyelination that differ from most other available models of multiple sclerosis (MS) in that they represent a mixture of...
4.
Minciacchi V, Spinelli C, Reis-Sobreiro M, Cavallini L, You S, Zandian M, et al.
Cancer Res . 2017 Feb; 77(9):2306-2317. PMID: 28202510
Communication between cancer cells and the tumor microenvironment results in the modulation of complex signaling networks that facilitate tumor progression. Here, we describe a new mechanism of intercellular communication originating...
5.
Minciacchi V, You S, Spinelli C, Morley S, Zandian M, Aspuria P, et al.
Oncotarget . 2015 Apr; 6(13):11327-41. PMID: 25857301
Large oncosomes (LO) are atypically large (1-10 µm diameter) cancer-derived extracellular vesicles (EVs), originating from the shedding of membrane blebs and associated with advanced disease. We report that 25% of...
6.
Mott K, Maazi H, Allen S, Zandian M, Matundan H, Ghiasi Y, et al.
Immunobiology . 2014 Dec; 220(4):518-24. PMID: 25468565
Recently, we have reported that CD8α(+) DCs, rather than CD8(+) T cells, are involved in the establishment and maintenance of HSV-1 latency in the trigeminal ganglia (TG) of ocularly infected...
7.
Jouanneau E, Black K, Veiga L, Cordner R, Goverdhana S, Zhai Y, et al.
Cancer Immunol Immunother . 2014 Jun; 63(9):911-24. PMID: 24893855
Background: Cancer vaccines reproducibly cure laboratory animals and reveal encouraging trends in brain tumor (glioma) patients. Identifying parameters governing beneficial vaccine-induced responses may lead to the improvement of glioma immunotherapies....
8.
Mott K, Allen S, Zandian M, Konda B, Sharifi B, Jones C, et al.
PLoS One . 2014 Apr; 9(4):e93444. PMID: 24695322
It is generally accepted that CD8 T cells play the key role to maintain HSV-1 latency in trigeminal ganglia of ocularly infected mice. Yet, comparably little is known about the...
9.
Mott K, Allen S, Zandian M, Ghiasi H
J Virol . 2014 Mar; 88(12):6599-610. PMID: 24672046
Unlabelled: The latency-associated transcript (LAT) of herpes simplex virus 1 (HSV-1), CD8α(+) dendritic cells (DCs), and programmed death 1 (PD-1) have all been implicated in the HSV-1 latency-reactivation cycle. It...
10.
Mott K, Allen S, Zandian M, Akbari O, Hamrah P, Maazi H, et al.
PLoS One . 2014 Jan; 9(1):e87617. PMID: 24475315
CD80 plays a critical role in stimulation of T cells and subsequent control of infection. To investigate the effect of CD80 on HSV-1 infection, we constructed a recombinant HSV-1 virus...