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Manami Amanai

Explore the profile of Manami Amanai including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 271
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Recent Articles
1.
Suzuki T, Suzuki E, Yoshida N, Kubo A, Li H, Okuda E, et al.
Development . 2010 Aug; 137(19):3281-91. PMID: 20724447
The oocytes of vertebrates are typically arrested at metaphase II (mII) by the cytostatic factor Emi2 until fertilization. Regulatory mechanisms in Xenopus Emi2 (xEmi2) are understood in detail but contrastingly...
2.
Yoshida N, Amanai M, Fukui T, Kajikawa E, Brahmajosyula M, Iwahori A, et al.
Development . 2007 Oct; 134(21):3941-52. PMID: 17933795
Mammalian metaphase II (mII) exit and embryogenesis are induced at fertilisation by a signal thought to come from the sperm protein, phospholipase C-zeta (PLCZ1). Meiotic progression can also be triggered...
3.
Zhang S, Cagatay T, Amanai M, Zhang M, Kline J, Castrillon D, et al.
Mol Cell Biol . 2007 Apr; 27(12):4454-64. PMID: 17438140
Gradients of Wnt/beta-catenin signaling coordinate development and physiological homeostasis in metazoan animals. Proper embryonic development of the fruit fly Drosophila melanogaster requires the Naked cuticle (Nkd) protein to attenuate a...
4.
Yoshida N, Brahmajosyula M, Shoji S, Amanai M, Perry A
Dev Biol . 2006 Sep; 301(2):464-77. PMID: 16989800
In mammalian fertilization, paternal chromatin is exhaustively remodeled, yet the maternal contribution to this process is unknown. To address this, we prevented the induction of meiotic exit by spermatozoa and...
5.
Amanai M, Shoji S, Yoshida N, Brahmajosyula M, Perry A
Biol Reprod . 2006 Sep; 75(6):891-8. PMID: 16943363
The manipulation of mammalian metaphase II (mII) oocytes has illuminated the mechanisms of fertilization and early embryogenesis and is central to nuclear transfer. Although RNA interference (RNAi) would greatly facilitate...
6.
Amanai M, Brahmajosyula M, Perry A
Biol Reprod . 2006 Sep; 75(6):877-84. PMID: 16943360
Prototypical microRNAs (miRNAs) are 21 approximately 25-base-pair RNAs that regulate differentiation, carcinogenesis, and pluripotency by eliminating mRNAs or blocking their translation, in a process that is collectively termed RNA interference...
7.
Waldrop S, Chan C, Cagatay T, Zhang S, Rousset R, Mack J, et al.
Genetics . 2006 Jul; 174(1):331-48. PMID: 16849595
Wnt/beta-catenin signals orchestrate cell fate and behavior throughout the animal kingdom. Aberrant Wnt signaling impacts nearly the entire spectrum of human disease, including birth defects, cancer, and osteoporosis. If Wnt...
8.
Shoji S, Yoshida N, Amanai M, Ohgishi M, Fukui T, Fujimoto S, et al.
EMBO J . 2006 Feb; 25(4):834-45. PMID: 16456547
Fertilizable mammalian oocytes are arrested at the second meiotic metaphase (mII) by the cyclinB-Cdc2 heterodimer, maturation promoting factor (MPF). MPF is stabilized via the activity of an unidentified cytostatic factor...
9.
Fujimoto S, Yoshida N, Fukui T, Amanai M, Isobe T, Itagaki C, et al.
Dev Biol . 2004 Sep; 274(2):370-83. PMID: 15385165
Mammalian sperm-borne oocyte activating factor (SOAF) induces oocyte activation from a compartment that engages the oocyte cytoplasm, but it is not known how. A SOAF-containing extract (SE) was solubilized from...