Manabu Nagao
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Explore the profile of Manabu Nagao including associated specialties, affiliations and a list of published articles.
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43
Citations
977
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Recent Articles
1.
Kuwahara N, Nagao M, Shinohara M, Kaneshiro K, Emoto T, Yoshida T, et al.
Hypertension
. 2025 Mar;
PMID: 40047081
Background: ATP citrate lyase (ACLY) is a key enzyme in de novo lipogenesis that generates acetyl-CoA from citrate. Although fatty acids are required for energy production and biomass synthesis in...
2.
Ujiro S, Fujimoto W, Takemoto M, Kuroda K, Yamashita S, Imanishi J, et al.
Circ J
. 2025 Mar;
PMID: 40024800
Background: With the aging of the population, the number of patients with chronic heart failure (CHF) and comorbidities is increasing in Japan. Among the comorbidities, cardiorenal anemia syndrome (CRAS) is...
3.
Suzuki Y, Emoto T, Sato S, Yoshida T, Shoda M, Endoh H, et al.
Commun Biol
. 2024 Dec;
7(1):1601.
PMID: 39622943
Atrial fibrillation (AF) is strongly associated with strokes, heart failure, and increased mortality. This study aims to identify the monocyte-macrophage heterogeneity and interactions of these cells with non-immune cells, and...
4.
Odajima S, Fujimoto W, Takegami M, Nishimura K, Iwasaki M, Okuda M, et al.
J Am Heart Assoc
. 2024 Sep;
13(19):e034793.
PMID: 39344672
Background: Stage B heart failure (HF) refers to structural heart disease without signs or symptoms of HF, so that early intervention may delay or prevent the onset of overt HF....
5.
Iino T, Nagao M, Tanaka H, Yoshikawa S, Asakura J, Nishimori M, et al.
Sci Rep
. 2024 Sep;
14(1):20508.
PMID: 39227655
The pathophysiology of variant transthyretin (TTR) amyloidosis (ATTRv) is associated with destabilizing mutations in the TTR tetramer. However, why TTR with a wild-type genetic sequence misfolds and aggregates in wild-type...
6.
Li R, Zhang S, Otsuguro S, Nagao M, Matsuda A, Thapa J, et al.
Biochem Biophys Res Commun
. 2024 Aug;
736:150461.
PMID: 39128263
To understand why Chlamydia trachomatis (Ct) (L2/434/Bu) favors hypoxia, we examined the dynamics of infected cells using a glycolysis-related PCR array and metabolomic analysis, along with the perturbation of nucleotide...
7.
Tanaka H, Ishida T, Emoto T, Nagao M, Izawa Y, Fukuda T, et al.
Circ J
. 2024 Jul;
88(9):1502-1508.
PMID: 39019582
The 88Annual Scientific Meeting of the Japanese Circulation Society (JCS2024) was held from Friday, March 8to Sunday, March 10in Kobe, Japan. The main theme of this 3-day meeting was "The...
8.
Seto Y, Nagao M, Iino T, Harada A, Murakami K, Miwa K, et al.
J Appl Lab Med
. 2024 Apr;
9(4):728-740.
PMID: 38574000
Background: Although low high-density lipoprotein cholesterol (HDL-C) levels are a common metabolic abnormality associated with insulin resistance, their role in cardiovascular risk stratification remains controversial. Recently, we developed a simple,...
9.
Nishimori M, Hayasaka N, Otsui K, Inoue N, Asakura J, Nagao M, et al.
Sci Rep
. 2024 Feb;
14(1):4178.
PMID: 38378892
Stress has garnered significant attention as a prominent risk factor for inflammation-related diseases, particularly cardiovascular diseases (CVDs). However, the precise mechanisms underlying stress-driven CVDs remain elusive, thereby impeding the development...
10.
Fujimoto W, Odajima S, Okamoto H, Iwasaki M, Nagao M, Konishi A, et al.
Circ J
. 2024 Feb;
88(5):732-739.
PMID: 38369348
Background: Early detection and intervention for preclinical heart failure (HF) are crucial for restraining the potential increase in patients with HF. Thus, we designed and conducted a single-center retrospective cohort...