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Manabu Higaki

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Citations 103
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Recent Articles
1.
Higaki M, Wada H, Mikura S, Yasutake T, Nakamura M, Niikura M, et al.
Exp Lung Res . 2015 Dec; 41(10):525-34. PMID: 26651880
Aim Of The Study: Interleukin (IL)-10 is an anti-inflammatory cytokine, but its role in cigarette smoke (CS)-induced inflammation and chronic obstructive pulmonary disease (COPD) has not been fully elucidated. The...
2.
Yasutake T, Wada H, Higaki M, Nakamura M, Honda K, Watanabe M, et al.
F1000Res . 2014 Mar; 2:78. PMID: 24627774
Objective And Design: The histone acetylation processes, which are believed to play a critical role in the regulation of many inflammatory genes, are reversible and regulated by histone acetyltransferases (HATs),...
3.
Higaki M, Ishida M, Nakamoto Y, Saraya T
Intern Med . 2013 Aug; 52(15):1757-8. PMID: 23903517
No abstract available.
4.
Higaki M, Kurai D, Ito A, Saraya T
BMJ Case Rep . 2013 May; 2013. PMID: 23709555
A 59-year-old man presented with hypohydrosis in his left upper extremity and left hand, and experienced difficulty in gripping the steering wheel while driving. One year prior to admission, he...
5.
Kobayashi Y, Wada H, Rossios C, Takagi D, Higaki M, Mikura S, et al.
J Pharmacol Exp Ther . 2013 Jan; 345(1):76-84. PMID: 23359665
Macrolides are reported to reduce exacerbation of chronic inflammatory respiratory disease, such as chronic obstructive pulmonary disease (COPD), and also show anti-inflammatory effects in vitro and in vivo. However the...
6.
Nakamoto K, Koide T, Nagatomo T, Tamura M, Higaki M, Takata S, et al.
Kansenshogaku Zasshi . 2011 Aug; 85(4):366-9. PMID: 21861440
A 70-year-old man with diabetes mellitus seen for fever, right chest pain, and right-lung field consolidation on chest X-ray was found in thoracoabdominal computed tomography (CT) to have variable-sized nodules...
7.
Takata S, Wada H, Tamura M, Koide T, Higaki M, Mikura S, et al.
Biomarkers . 2011 Aug; 16(6):530-535. PMID: 21854219
Context: In management of community-acquired pneumonia (CAP), excellent biomarkers for inflammation would be helpful in our practice. Objectives: Kinetics of c-reactive protein (CRP) and serum amyloid A (SAA) was characterized,...
8.
Mikura S, Wada H, Higaki M, Yasutake T, Ishii H, Kamiya S, et al.
Transl Res . 2011 Jun; 158(1):30-7. PMID: 21708354
The effect of erythromycin on the inflammation caused by exposure to cigarette smoke was investigated in this study. Mice were exposed either to cigarette smoke or to environmental air (control),...
9.
Hirao S, Wada H, Nakagaki K, Saraya T, Kurai D, Mikura S, et al.
FEMS Immunol Med Microbiol . 2011 Mar; 62(2):182-9. PMID: 21395697
Recently, combination treatment with a macrolide and a steroid for Mycoplasma pneumoniae (Mp) pneumonia has been reported to be effective. Thus, the effect of this combination on a mouse model...
10.
Saraya T, Kurai D, Ariga M, Nakamoto K, Koide T, Tamura M, et al.
Intern Med . 2009 Jun; 48(12):1065-8. PMID: 19525600
A 92-year-old man who had been hospitalized for dementia developed sudden-onset bilious vomiting accompanied by a fever of 40 degrees C. Physical examination revealed an 8 cm diameter pulsatile mass...