Mana Higashihara
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Explore the profile of Mana Higashihara including associated specialties, affiliations and a list of published articles.
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61
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Recent Articles
1.
Kurihara M, Satoh K, Shimasaki R, Hatano K, Ohse K, Taira K, et al.
NPJ Parkinsons Dis
. 2024 Oct;
10(1):190.
PMID: 39433540
Although α-synuclein seed amplification assays (α-syn SAA) are promising, its sensitivity may be affected by heterogeneity among patients with Lewy body disease (LBD). We evaluated whether α-syn SAA sensitivity is...
2.
van den Bos M, Menon P, Pavey N, Higashihara M, Kiernan M, Vucic S
Brain
. 2024 Oct;
PMID: 39385724
Cortical hyperexcitability is a key pathogenic feature of amyotrophic lateral sclerosis (ALS), believed to be mediated through complex interplay of cortical interneurons. To date, there has been no technological approach...
3.
Shimasaki R, Kurihara M, Hatano K, Goto R, Taira K, Ihara R, et al.
Parkinsonism Relat Disord
. 2024 Sep;
128:107129.
PMID: 39241507
Cerebrospinal fluid (CSF) homovanillic acid (HVA) and 5-hydroxyindole acetic acid (5-HIAA), dopamine and serotonin metabolites, are decreased in Parkinson's disease (PD). Although some reported associations between HVA and striatal dopamine...
4.
Pavey N, Hannaford A, Higashihara M, van den Bos M, Geevasinga N, Vucic S, et al.
J Neurol Neurosurg Psychiatry
. 2024 Aug;
PMID: 39137976
Background: Cortical inexcitability, a less studied feature of upper motor neuron (UMN) dysfunction in amyotrophic lateral sclerosis (ALS), was identified in a large cross-sectional cohort of ALS patients and their...
5.
Kondo S, Kurihara M, Higashihara M, Hara M, Nishina Y, Iwakiri R, et al.
Geriatr Gerontol Int
. 2024 Jun;
24(7):739-742.
PMID: 38860537
An 81-year-old woman presented with statin-induced anti-HMGCR immune-mediated necrotizing myopathy. Treatment was successful without complications with a reduced oral steroid dosage from the current consensus for all ages and backgrounds....
6.
Dharmadasa T, Pavey N, Tu S, Menon P, Huynh W, Mahoney C, et al.
Clin Neurophysiol
. 2024 May;
163:68-89.
PMID: 38705104
Identifying upper motor neuron (UMN) dysfunction is fundamental to the diagnosis and understanding of disease pathogenesis in motor neuron disease (MND). The clinical assessment of UMN dysfunction may be difficult,...
7.
Arakawa A, Goto R, Higashihara M, Hiroyoshi Y, Shioya A, Hara M, et al.
Neuropathology
. 2024 Apr;
44(5):376-387.
PMID: 38558069
Argyrophilic grain disease (AGD) is one of the major pathological backgrounds of senile dementia. Dementia with grains refers to cases of dementia for which AGD is the sole background pathology...
8.
Higashihara M, Pavey N, Menon P, van den Bos M, Shibuya K, Kuwabara S, et al.
Eur J Neurol
. 2024 Mar;
31(7):e16281.
PMID: 38504632
Background And Purpose: Cortical hyperexcitability has been identified as a diagnostic and pathogenic biomarker of amyotrophic lateral sclerosis (ALS). Cortical excitability is assessed by transcranial magnetic stimulation (TMS), a non-invasive...
9.
Funakawa K, Kurihara M, Takahashi K, Higashihara M, Hara M, Mitsutake A, et al.
J Neurol Sci
. 2024 Feb;
458:122915.
PMID: 38326182
No abstract available.
10.
Pavey N, Hannaford A, Higashihara M, van den Bos M, Kiernan M, Menon P, et al.
Clin Neurophysiol
. 2023 Nov;
156:175-182.
PMID: 37967511
Objective: Utility of the split hand index (SI) in amyotrophic lateral sclerosis (ALS) has been reported when using the compound muscle action potential (CMAP) amplitude method (SI). A motor unit...