Mamana Mbiyavanga
Overview
Explore the profile of Mamana Mbiyavanga including associated specialties, affiliations and a list of published articles.
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19
Citations
313
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Recent Articles
1.
Nanjala R, Mbiyavanga M, Hashim S, de Villiers S, Mulder N
PLoS One
. 2023 Sep;
18(9):e0291437.
PMID: 37768905
The Human Leukocyte Antigen (HLA) region plays an important role in autoimmune and infectious diseases. HLA is a highly polymorphic region and thus difficult to impute. We, therefore, sought to...
2.
Sengupta D, Botha G, Meintjes A, Mbiyavanga M, Hazelhurst S, Mulder N, et al.
Cell Genom
. 2023 Jun;
3(6):100332.
PMID: 37388906
Based on evaluations of imputation performed on a genotype dataset consisting of about 11,000 sub-Saharan African (SSA) participants, we show Trans-Omics for Precision Medicine (TOPMed) and the African Genome Resource...
3.
Nanjala R, Mbiyavanga M, Hashim S, de Villiers S, Mulder N
bioRxiv
. 2023 Feb;
PMID: 36747714
Author Summary: For studies that associate a particular HLA type to a phenotypic trait for instance HIV susceptibility or control, genotype imputation remains the main method for acquiring a larger...
4.
Sinkala M, Elsheikh S, Mbiyavanga M, Cullinan J, Mulder N
Commun Biol
. 2023 Jan;
6(1):49.
PMID: 36641522
Pulmonary function is an indicator of well-being, and pulmonary pathologies are the third major cause of death worldwide. We analysed the UK Biobank genome-wide association summary statistics of pulmonary function...
5.
Dyke S, Connor K, Nembaware V, Munung N, Reinold K, Kerry G, et al.
Neuroinformatics
. 2022 Dec;
21(1):89-100.
PMID: 36520344
We previously proposed a structure for recording consent-based data use 'categories' and 'requirements' - Consent Codes - with a view to supporting maximum use and integration of genomic research datasets,...
6.
da Rocha J, Othman H, Botha G, Cottino L, Twesigomwe D, Ahmed S, et al.
Front Pharmacol
. 2021 Nov;
12:634016.
PMID: 34721006
Investigating variation in genes involved in the absorption, distribution, metabolism, and excretion (ADME) of drugs are key to characterizing pharmacogenomic (PGx) relationships. ADME gene variation is relatively well characterized in...
7.
Choudhury A, Aron S, Botigue L, Sengupta D, Botha G, Bensellak T, et al.
Nature
. 2021 Apr;
592(7856):E26.
PMID: 33846614
No abstract available.
8.
Choudhury A, Aron S, Botigue L, Sengupta D, Botha G, Bensellak T, et al.
Nature
. 2020 Oct;
586(7831):741-748.
PMID: 33116287
The African continent is regarded as the cradle of modern humans and African genomes contain more genetic variation than those from any other continent, yet only a fraction of the...
9.
Ahmed A, Mpangase P, Panji S, Baichoo S, Souilmi Y, Fadlelmola F, et al.
AAS Open Res
. 2020 May;
1:9.
PMID: 32382696
The need for portable and reproducible genomics analysis pipelines is growing globally as well as in Africa, especially with the growth of collaborative projects like the Human Health and Heredity...
10.
Kumuthini J, Zass L, Panji S, Salifu S, Kayondo J, Nembaware V, et al.
BMC Bioinformatics
. 2020 Jan;
20(1):741.
PMID: 31888443
Background: Currently, formal mechanisms for bioinformatics support are limited. The H3Africa Bioinformatics Network has implemented a public and freely available Helpdesk (HD), which provides generic bioinformatics support to researchers through...