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Malgorzata Brindell

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Articles 43
Citations 309
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Recent Articles
1.
Gajda-Morszewski P, Poznanska A, Federyga E, Sciuk A, Brindell M
Molecules . 2024 Jun; 29(12). PMID: 38930801
The growth of , a member of the genus, which plays a crucial role in the bacterial microbiome of the gut, is significantly influenced by manganese ions. They can be...
2.
Oszajca M, Flejszar M, Szura A, Drozdz P, Brindell M, Kurpiewska K
Front Chem . 2024 Apr; 12:1371637. PMID: 38638879
This study presents a comprehensive structural analysis of the adducts formed upon the reaction of two Ru(III) complexes [HIsq][-RuCl(dmso)(Isq)] () and [HInd][-RuCl(dmso)(HInd)] () (where HInd-indazole, Isq-isoquinoline, analogs of NAMI-A) and...
3.
Sumithaa C, Gajda-Morszewski P, Ishaniya W, Khamrang T, Velusamy M, Bhuvanesh N, et al.
Dalton Trans . 2023 Dec; 53(3):966-985. PMID: 38054338
Despite the enormous efforts made over the past two decades to develop metallodrugs and nanocarriers for metallodrug delivery, there are still few precise strategies that aim to optimize the design...
4.
Gajda-Morszewski P, Poznanska A, Yus C, Arruebo M, Brindell M
Nanomaterials (Basel) . 2023 Sep; 13(18). PMID: 37764553
Lactoferrin (Lf) is a globular glycoprotein found mainly in milk. It has a very high affinity for iron(III) ions, and its fully saturated form is called holoLf. The antimicrobial, antiviral,...
5.
Gurgul I, Janczy-Cempa E, Mazuryk O, Lekka M, Lomzik M, Suzenet F, et al.
J Med Chem . 2022 Jul; 65(15):10459-10470. PMID: 35895090
The effect of polypyridyl Ru(II) complexes on the ability of cancer cells to migrate and invade, two features important in the formation of metastases, is evaluated. studies are carried out...
6.
Gurgul I, Mazuryk O, Stachyra K, Olszanecki R, Lekka M, Lomzik M, et al.
Int J Mol Sci . 2022 Jul; 23(14). PMID: 35887054
The use of polypyridyl Ru complexes to inhibit metastasis is a novel approach, and recent studies have shown promising results. We have reported recently that Ru (II) complexes gathering two...
7.
Sumithaa C, Manjunathan T, Mazuryk O, Peters S, Pillai R, Brindell M, et al.
ACS Appl Bio Mater . 2022 Jul; 5(7):3241-3256. PMID: 35786838
The organometallic compounds are prospective candidates in the row of developing metallochemotherapeutics with the aim of overcoming the limitations of platinum drugs. In order to explore the anticancer properties of...
8.
Janczy-Cempa E, Mazuryk O, Kania A, Brindell M
Cancers (Basel) . 2022 Jun; 14(11). PMID: 35681666
Hypoxia is one of the hallmarks of the tumor microenvironment and can be used in the design of targeted therapies. Cellular adaptation to hypoxic stress is regulated by hypoxia-inducible factor...
9.
Mazuryk O, Janczy-Cempa E, Lagosz J, Rutkowska-Zbik D, Machnicka A, Krasowska A, et al.
Dalton Trans . 2022 Jan; 51(5):1888-1900. PMID: 35018930
The purpose of this study was to investigate the correlation between the spectroscopic and photophysical properties of Ru(II) polypyridyl complexes and their photodynamic activity . A series of Ru(II) polypyridyl...
10.
Brindell M, Gurgul I, Janczy-Cempa E, Gajda-Morszewski P, Mazuryk O
J Inorg Biochem . 2021 Nov; 226:111652. PMID: 34741931
In recent years, Ru polypyridyl complexes have been intensively studied for their anticancer activity. The vast majority of research focuses on assessing their cytotoxic activity, as well as targeting cancer...