Malene Jackerott
Overview
Explore the profile of Malene Jackerott including associated specialties, affiliations and a list of published articles.
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10
Citations
176
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Recent Articles
1.
Olesen U, Pedersen K, Togsverd-Bo K, Biskup E, Nielsen A, Jackerott M, et al.
Lasers Surg Med
. 2024 Feb;
56(3):239-248.
PMID: 38311811
Background: Systemically delivered hedgehog inhibitors including vismodegib and sonidegib are widely used to treat basal cell carcinomas (BCCs). Ablative fractional laser (AFL)-assisted topical delivery of vismodegib has been demonstrated in...
2.
Tang Q, Fakih H, Zain Ui Abideen M, Hildebrand S, Afshari K, Gross K, et al.
Nat Commun
. 2023 Nov;
14(1):7099.
PMID: 37925520
Inhibition of Janus kinase (JAK) family enzymes is a popular strategy for treating inflammatory and autoimmune skin diseases. In the clinic, small molecule JAK inhibitors show distinct efficacy and safety...
3.
Lejeune P, Cruciani V, Berg-Larsen A, Schlicker A, Mobergslien A, Bartnitzky L, et al.
J Immunother Cancer
. 2021 Oct;
9(10).
PMID: 34615703
Background: Targeted thorium-227 conjugates (TTCs) are an emerging class of targeted alpha therapies (TATs). Their unique mode of action (MoA) is the induction of difficult-to-repair clustered DNA double-strand breaks. However,...
4.
Javanbakht H, Mueller H, Walther J, Zhou X, Lopez A, Pattupara T, et al.
Mol Ther Nucleic Acids
. 2018 Jun;
11:441-454.
PMID: 29858079
Chronic hepatitis B infection (CHB) is an area of high unmet medical need. Current standard-of-care therapies only rarely lead to a functional cure, defined as durable hepatitis B surface antigen...
5.
Bang-Berthelsen C, Holm T, Pyke C, Simonsen L, Sokilde R, Pociot F, et al.
Inflamm Bowel Dis
. 2016 Aug;
22(9):2078-97.
PMID: 27542128
Background: Beneficial roles for glucagon-like peptide 1 (GLP-1)/GLP-1R signaling have recently been described in diseases, where low-grade inflammation is a common phenomenon. We investigated the effects of GLP-1 in Brunner's...
6.
Jackerott M, Moldrup A, Thams P, Galsgaard E, Knudsen J, Lee Y, et al.
Diabetes
. 2006 Sep;
55(10):2705-12.
PMID: 17003334
Pancreatic beta-cell growth and survival and insulin production are stimulated by growth hormone and prolactin through activation of the transcription factor signal transducer and activator of transcription (STAT)5. To assess...
7.
Jackerott M, Lee Y, Mollgard K, Kofod H, Jensen J, Rohleder S, et al.
Endocrinology
. 2006 Sep;
147(12):5752-9.
PMID: 16973727
Trefoil factors (TFFs) 1, 2, and 3 are expressed in mucosal epithelia. TFFs are particular abundant in the intestine in which they play a crucial role in maintenance and restitution...
8.
Lamotte L, Jackerott M, Bucchini D, Jami J, Joshi R, Deltour L
Transgenic Res
. 2004 Dec;
13(5):463-73.
PMID: 15587270
We report here knock-in of diphteria toxin A chain (dta) gene at the Ins2 locus, using the strategy previously employed to insert lacZ under control of the Ins2 promoter. Mutant...
9.
Baudry A, Jackerott M, Lamothe B, Kozyrev S, Leroux L, Durel B, et al.
Gene
. 2002 Dec;
299(1-2):219-25.
PMID: 12459269
Insulin receptor (IR)-deficient mice develop severe diabetes mellitus, diabetic ketoacidosis (DKA) and liver steatosis and die within 1 week after birth. We examined in this work whether the metabolic phenotype...
10.
Baudry A, Leroux L, Jackerott M, Joshi R
EMBO Rep
. 2002 Apr;
3(4):323-8.
PMID: 11943762
Non-insulin-dependent diabetes mellitus (NIDDM) is a complex heterogeneous polygenic disease characterized mainly by insulin resistance and pancreatic beta-cell dysfunction. In recent years, several genetically engineered mouse models have been developed...