Malay Patra
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Explore the profile of Malay Patra including associated specialties, affiliations and a list of published articles.
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61
Citations
781
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Recent Articles
1.
Li Y, Wang C, Patra M, Chen Y, Yang W, Yuan H
Nucleic Acids Res
. 2025 Feb;
53(4).
PMID: 39997218
Human polynucleotide phosphorylase (hPNPase) is a 3'-to-5' exoribonuclease located in mitochondria, where it plays crucial roles in RNA degradation and RNA import. Mutations in hPNPase can impair these functions, leading...
2.
M M, Chhatar S, Dey S, Panda T, Chakraborty S, Ray P, et al.
ACS Med Chem Lett
. 2024 Sep;
15(9):1482-1490.
PMID: 39291013
Cancer is a multifaceted disease involving various pathological processes, including uncontrolled proliferation, development of resistance, angiogenesis, metastasis, etc. Therefore, chemotherapeutic agents capable of simultaneously inhibiting proliferation, circumventing chemoresistance, and inhibiting...
3.
Phadte P, Bishnu A, Dey P, M M, Mehrotra M, Singh P, et al.
J Exp Clin Cancer Res
. 2024 Aug;
43(1):222.
PMID: 39123206
Background: The mechanisms enabling dynamic shifts between drug-resistant and drug-sensitive states in cancer cells are still underexplored. This study investigated the role of targeted autophagic protein degradation in regulating ovarian...
4.
Shelar D, Malankar G, Salunkhe S, Manikandan M, Chavan A, Pinjari R, et al.
Bioorg Chem
. 2024 Jun;
150:107568.
PMID: 38905887
Phenylselenide based BODIPY probe was successfully synthesized and characterized by NMR spectroscopic techniques (H, C and Se NMR), mass spectrometry and single crystal XRD. Surprisingly, crystal packing diagram of the...
5.
Panda T, Patra M
ChemMedChem
. 2024 May;
19(17):e202400196.
PMID: 38757478
The search for better chemotherapeutic drugs to alleviate the deficiencies of existing platinum (Pt) drugs has picked up the pace in the millennium. There has been a disparate effort to...
6.
Das S, Joshi P, Patra M
Inorg Chem
. 2023 Nov;
62(48):19720-19733.
PMID: 37974075
Chemotherapy with the cytotoxic platinum (Pt) drugs cisplatin, carboplatin, and oxaliplatin is the mainstay of anticancer therapy in the clinic. The antitumor activity of Pt drugs originates from their ability...
7.
M M, Chhatar S, Gadre S, Paul S, Vaidya S, Khatri S, et al.
Chemistry
. 2023 Oct;
30(4):e202302720.
PMID: 37888749
The impact of kinetic lability or reactivity on in vitro cytotoxicity, stability in plasma, in vivo tumor and tissue accumulation, and antitumor efficacy of functional platinum(II) (Pt) anticancer agents containing...
8.
Goel N, Srivastav S, Patel A, Shirsath A, Panda T, Patra M, et al.
Microbiol Spectr
. 2023 Oct;
11(6):e0222523.
PMID: 37855642
Energy generation pathways are a potential avenue for the development of novel antibiotics. However, bacteria possess remarkable resilience due to the compensatory pathways, which presents a challenge in this direction....
9.
Gadre S, M M, Chakraborty G, Rayrikar A, Paul S, Patra C, et al.
J Med Chem
. 2023 Oct;
66(19):13481-13500.
PMID: 37784224
While the phenomenal clinical success of blockbuster platinum (Pt) drugs is highly encouraging, the inherent and acquired resistance and dose-limiting side effects severely limit their clinical application. To find a...
10.
Panda T, M M, Vaidya S, Chhatar S, Sinha S, Mehrotra M, et al.
Angew Chem Int Ed Engl
. 2023 Jun;
62(38):e202303958.
PMID: 37314332
Even in the modern era of precision medicine and immunotherapy, chemotherapy with platinum (Pt) drugs remains among the most commonly prescribed medications against a variety of cancers. Unfortunately, the broad...