Malabi M Venkatesan
Overview
Explore the profile of Malabi M Venkatesan including associated specialties, affiliations and a list of published articles.
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Articles
39
Citations
682
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Recent Articles
1.
Ruamsap N, Imerbsin R, Khanijou P, Gonwong S, Oransathit W, Barnoy S, et al.
Front Microbiol
. 2024 Sep;
15:1454338.
PMID: 39309527
Shigellosis remains a significant global health challenge, particularly in Asia and Africa, where it is a major cause of morbidity and mortality among children. Despite the urgent need, the development...
2.
Venkatesan M, Barnoy S, Frenck R, McNeal M, Baqar S
PLoS One
. 2024 Jan;
19(1):e0290987.
PMID: 38232106
B memory (BM) cell responses were evaluated using peripheral blood mononuclear cells that were collected and cryopreserved during a Phase 1 trial of two live Shigella sonnei vaccine candidates WRSs2...
3.
Venkatesan M, Ballou C, Barnoy S, McNeal M, El-Khorazaty J, Frenck R, et al.
PLoS One
. 2021 Nov;
16(11):e0259361.
PMID: 34793505
The levels of antigen-specific Antibodies in Lymphocyte Supernatant (ALS) using an ELISA are being used to evaluate mucosal immune responses as an alternate to measuring the number of Antibody Secreting...
4.
Sarker P, Mily A, Ara A, Haque F, Maier N, Wierzba T, et al.
J Infect Dis
. 2021 Aug;
224(12 Suppl 2):S829-S839.
PMID: 34374425
Background: We demonstrated in a randomized placebo-controlled trial that WRSS1, a live oral Shigella sonnei vaccine candidate, is safe in Bangladeshi adults and children, and elicits antigen-specific antibodies. Here, we...
5.
Clarkson K, Frenck Jr R, Dickey M, Suvarnapunya A, Chandrasekaran L, Weerts H, et al.
mSphere
. 2020 Sep;
5(5).
PMID: 32968012
is a major cause of moderate to severe diarrhea largely affecting children (<5 years old) living in low- and middle-income countries. Several vaccine candidates are in development, and controlled human...
6.
Establishment of a Controlled Human Infection Model with a Lyophilized Strain of Shigella sonnei 53G
Frenck Jr R, Dickey M, Suvarnapunya A, Chandrasekaran L, Kaminski R, Clarkson K, et al.
mSphere
. 2020 Sep;
5(5).
PMID: 32968005
Controlled human infection models (CHIMs) are useful for vaccine development. To improve on existing models, we developed a CHIM using a lyophilized preparation of strain 53G produced using current good...
7.
Raqib R, Sarker P, Zaman K, Alam N, Wierzba T, Maier N, et al.
Hum Vaccin Immunother
. 2019 Feb;
15(6):1326-1337.
PMID: 30794051
live vaccine candidate, WRSS1, which was previously evaluated in US, Israeli and Thai volunteers, was administered orally to Bangladeshi adults and children to assess its safety, clinical tolerability and immunogenicity....
8.
Frenck Jr R, Baqar S, Alexander W, Dickey M, McNeal M, El-Khorazaty J, et al.
Vaccine
. 2018 Jul;
36(32 Pt B):4880-4889.
PMID: 30037478
Effective vaccines are needed to combat diarrheal diseases due to Shigella. Two live oral S. sonnei vaccine candidates, WRSs2 and WRSs3, attenuated principally by the lack of spreading ability, as...
9.
Barnoy S, Gancz H, Zhu Y, Honnold C, Zurawski D, Venkatesan M
Gut Microbes
. 2017 Mar;
8(4):335-350.
PMID: 28277944
Shigella spp. causing bacterial diarrhea and dysentery are human enteroinvasive bacterial pathogens that are orally transmitted through contaminated food and water and cause bacillary dysentery. Although natural Shigella infections are...
10.
Pitisuttithum P, Islam D, Chamnanchanunt S, Ruamsap N, Khantapura P, Kaewkungwal J, et al.
Clin Vaccine Immunol
. 2016 May;
23(7):564-75.
PMID: 27146000
Live attenuated Shigella sonnei vaccine candidate WRSS1, previously tested in U.S. and Israeli volunteers, was evaluated in a population of adult Thai volunteers in which the organism is endemic. In...