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Makoto Tsunozaki

Explore the profile of Makoto Tsunozaki including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 1071
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Recent Articles
1.
Chalasani S, Chronis N, Tsunozaki M, Gray J, Ramot D, Goodman M, et al.
Nature . 2016 Jan; 533(7601):130. PMID: 26789243
No abstract available.
2.
Tsunozaki M, Lennertz R, Vilceanu D, Katta S, Stucky C, Bautista D
J Physiol . 2013 May; 591(13):3325-40. PMID: 23652591
In traditional medicine, the 'toothache tree' and other plants of the Zanthoxylum genus have been used to treat inflammatory pain conditions, such as toothache and rheumatoid arthritis. Here we examined...
3.
Gerhold K, Pellegrino M, Tsunozaki M, Morita T, Leitch D, Tsuruda P, et al.
PLoS One . 2013 Feb; 8(1):e55001. PMID: 23383028
Little is known about the molecular mechanisms underlying mammalian touch transduction. To identify novel candidate transducers, we examined the molecular and cellular basis of touch in one of the most...
4.
Bautista D, Pellegrino M, Tsunozaki M
Annu Rev Physiol . 2012 Oct; 75:181-200. PMID: 23020579
Tissue damage evokes an inflammatory response that promotes the removal of harmful stimuli, tissue repair, and protective behaviors to prevent further damage and encourage healing. However, inflammation may outlive its...
5.
Shinkai Y, Yamamoto Y, Fujiwara M, Tabata T, Murayama T, Hirotsu T, et al.
J Neurosci . 2011 Mar; 31(8):3007-15. PMID: 21414922
Animals facing conflicting sensory cues make a behavioral choice between competing alternatives through integration of the sensory cues. Here, we performed a genetic screen to identify genes important for the...
6.
Bendesky A, Tsunozaki M, Rockman M, Kruglyak L, Bargmann C
Nature . 2011 Mar; 472(7343):313-8. PMID: 21412235
Innate behaviours are flexible: they change rapidly in response to transient environmental conditions, and are modified slowly by changes in the genome. A classical flexible behaviour is the exploration-exploitation decision,...
7.
Lennertz R, Tsunozaki M, Bautista D, Stucky C
J Neurosci . 2010 Mar; 30(12):4353-61. PMID: 20335471
Hydroxy-alpha-sanshool, the active ingredient in plants of the prickly ash plant family, induces robust tingling paresthesia by activating a subset of somatosensory neurons. However, the subtypes and physiological function of...
8.
Tsunozaki M, Bautista D
Curr Opin Neurobiol . 2009 Aug; 19(4):362-9. PMID: 19683913
In the mammalian somatosensory system, mechanosensitive neurons mediate the senses of touch and pain. Among sensory modalities, mechanosensation has been the most elusive with regard to the identification of transduction...
9.
Tsunozaki M, Chalasani S, Bargmann C
Neuron . 2008 Sep; 59(6):959-71. PMID: 18817734
Innate chemosensory preferences are often encoded by sensory neurons that are specialized for attractive or avoidance behaviors. Here, we show that one olfactory neuron in Caenorhabditis elegans, AWC(ON), has the...
10.
Chalasani S, Chronis N, Tsunozaki M, Gray J, Ramot D, Goodman M, et al.
Nature . 2007 Nov; 450(7166):63-70. PMID: 17972877
Although many properties of the nervous system are shared among animals and systems, it is not known whether different neuronal circuits use common strategies to guide behaviour. Here we characterize...