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Makoto Sekihara

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Citations 178
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Recent Articles
1.
Bun K, Mode B, Susapu M, Salo J, Bjerum C, Payne M, et al.
PLoS Negl Trop Dis . 2025 Jan; 19(1):e0012128. PMID: 39869653
Background: WHO recommends two annual rounds of mass drug administration (MDA) with ivermectin, diethylcarbamazine, and albendazole (IDA) for lymphatic filariasis (LF) elimination in treatment naïve areas that are not co-endemic...
2.
Rainima-Qaniuci M, Lepaitai H, Bhagirov R, Padmasiri E, Naseri T, Thomsen R, et al.
Am J Trop Med Hyg . 2022 Mar; 106(5_Suppl):39-47. PMID: 35292579
We discuss the experience of some Pacific island countries in introducing the new WHO-recommended treatment protocol for lymphatic filariasis-a triple-drug therapy composed of ivermectin, diethylcarbamazine, and albendazole. The successful rollout...
3.
Fukuda N, Tachibana S, Ikeda M, Sakurai-Yatsushiro M, Balikagala B, Katuro O, et al.
Parasitol Int . 2020 Dec; 81:102277. PMID: 33370608
In Uganda, artemether-lumefantrine was introduced as an artemisinin-based combination therapy (ACT) for malaria in 2006. We have previously reported a moderate decrease in ex vivo efficacy of lumefantrine in Northern...
4.
Miotto O, Sekihara M, Tachibana S, Yamauchi M, Pearson R, Amato R, et al.
PLoS Pathog . 2020 Dec; 16(12):e1009133. PMID: 33320907
The rapid and aggressive spread of artemisinin-resistant Plasmodium falciparum carrying the C580Y mutation in the kelch13 gene is a growing threat to malaria elimination in Southeast Asia, but there is...
5.
Balikagala B, Sakurai-Yatsushiro M, Tachibana S, Ikeda M, Yamauchi M, Katuro O, et al.
Malar J . 2020 Feb; 19(1):76. PMID: 32070358
Background: Usage of chloroquine was discontinued from the treatment of Plasmodium falciparum infection in almost all endemic regions because of global spread of resistant parasites. Since the first report in...
6.
Yoshii A, Sekihara M, Furusawa T, Hombhanje F, Tsukahara T
Malar J . 2019 Feb; 18(1):42. PMID: 30786891
Background: To control and eventually eliminate vivax malaria, radical treatment with primaquine (PQ) is essential after completion of blood-stage treatment. Although in many malaria-endemic countries, village health volunteers (VHVs) are...
7.
Sekihara M, Tachibana S, Yamauchi M, Yatsushiro S, Tiwara S, Fukuda N, et al.
Malar J . 2018 Nov; 17(1):434. PMID: 30477515
Background: Chloroquine treatment for Plasmodium falciparum has been discontinued in almost all endemic regions due to the spread of resistant isolates. Reversal of chloroquine susceptibility after chloroquine discontinuation has been...
8.
Mita T, Hombhanje F, Takahashi N, Sekihara M, Yamauchi M, Tsukahara T, et al.
Sci Rep . 2018 Apr; 8(1):5565. PMID: 29615786
The ability of the human malarial parasite Plasmodium falciparum to adapt to environmental changes depends considerably on its ability to maintain within-population genetic variation. Strong selection, consequent to widespread antimalarial...
9.
Ikeda M, Kaneko M, Tachibana S, Balikagala B, Sakurai-Yatsushiro M, Yatsushiro S, et al.
Emerg Infect Dis . 2018 Mar; 24(4):718-726. PMID: 29553316
Because ≈90% of malaria cases occur in Africa, emergence of artemisinin-resistant Plasmodium falciparum in Africa poses a serious public health threat. To assess emergence of artemisinin-resistant parasites in Uganda during...
10.
Inoue Y, Takahashi D, Kondo N, Yoshii A, Sekihara M, Hombhanje F, et al.
Trans R Soc Trop Med Hyg . 2018 Feb; 111(11):490-496. PMID: 29425338
Background: Little is known about the association between the social capital of village health volunteers (VHVs) and their performance in relation to malarial care. Methods: Data came from 337 children...