Mahtab Moayeri
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Explore the profile of Mahtab Moayeri including associated specialties, affiliations and a list of published articles.
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99
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3918
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Recent Articles
1.
Bothra A, Perry M, Wei E, Moayeri M, Ma Q, Biamonte M, et al.
Sci Rep
. 2023 Dec;
13(1):22562.
PMID: 38110611
The detection of pathogens is critical for clinical diagnosis and public health surveillance. Detection is usually done with nucleic acid-based tests (NATs) and rapid antigen tests (e.g., lateral flow assays...
2.
Verma A, Moayeri M, Mocca C, OMard D, Ma Q, Leppla S, et al.
Vaccine
. 2022 Jun;
40(32):4318-4321.
PMID: 35710508
Anthrax protective antigen (PA), the receptor-binding component of anthrax toxin, elicits toxin-neutralizing antibodies which provide protection against anthrax disease. PA binds to two mammalian receptors, capillary morphogenesis protein-2 (CMG2) and...
3.
Bomfim C, Fisher L, Amaral E, Mittereder L, McCann K, Correa A, et al.
Front Cell Infect Microbiol
. 2022 May;
12:862582.
PMID: 35586249
Irg1 is an enzyme that generates itaconate, a metabolite that plays a key role in the regulation of inflammatory responses. Previous studies have implicated Irg1 as an important mediator in...
4.
Yang N, Isensee J, Neel D, Quadros A, Zhang H, Lauzadis J, et al.
Nat Neurosci
. 2021 Dec;
25(2):168-179.
PMID: 34931070
Bacterial products can act on neurons to alter signaling and function. In the present study, we found that dorsal root ganglion (DRG) sensory neurons are enriched for ANTXR2, the high-affinity...
5.
Merritt C, Chun E, Fattah R, Silva L, Ma Q, Moayeri M, et al.
J Biol Chem
. 2021 Dec;
298(1):101467.
PMID: 34871548
Bacillus anthracis lethal toxin and edema toxin are binary toxins that consist of a common cell-binding moiety, protective antigen (PA), and the enzymatic moieties, lethal factor (LF) and edema factor...
6.
Couse Z, Cui X, Li Y, Moayeri M, Leppla S, Eichacker P
Toxins (Basel)
. 2021 Jan;
13(1).
PMID: 33450877
Anti-toxin agents for severe infection will only be effective if they add to the benefit of the two mainstays of septic shock management, antibiotic therapy and titrated hemodynamic support. Both...
7.
Cui X, Wang J, Li Y, Couse Z, Risoleo T, Moayeri M, et al.
Am J Physiol Heart Circ Physiol
. 2020 Oct;
320(1):H36-H51.
PMID: 33064559
edema toxin (ET) inhibited lethal toxin-stimulated pulmonary artery pressure (Ppa) and increased lung cAMP levels in our previous study. We therefore examined whether ET inhibits hypoxic pulmonary vasoconstriction (HPV). Following...
8.
Mendenhall M, Liu S, Portley M, OMard D, Fattah R, Szabo R, et al.
Nat Microbiol
. 2020 Sep;
5(12):1464-1471.
PMID: 32895527
Anthrax lethal toxin (LT), produced by Bacillus anthracis, comprises a receptor-binding moiety, protective antigen and the lethal factor (LF) protease. Although LF is known to cleave mitogen-activated protein kinase kinases...
9.
Greaney A, Portley M, OMard D, Crown D, Maier N, Mendenhall M, et al.
J Leukoc Biol
. 2020 May;
108(3):773-786.
PMID: 32421904
Anthrax lethal toxin (LT) is a protease that activates the NLRP1b inflammasome sensor in certain rodent strains. Unlike better-studied sensors, relatively little is known about the priming requirements for NLRP1b....
10.
Vrentas C, Boggiatto P, Olsen S, Leppla S, Moayeri M
Innate Immun
. 2019 Nov;
26(4):301-311.
PMID: 31711335
Inflammasomes act as sensors of infection or damage to initiate immune responses. While extensively studied in rodents, understanding of livestock inflammasomes is limited. The NLRP1 inflammasome sensor in rodents is...