Maho Kanai
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Explore the profile of Maho Kanai including associated specialties, affiliations and a list of published articles.
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10
Citations
55
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Recent Articles
1.
Okamura Y, Gochi K, Ishikawa T, Hayashi T, Fuseya S, Suzuki R, et al.
Sci Rep
. 2024 Nov;
14(1):28774.
PMID: 39567640
Long-duration spaceflight creates a variety of stresses due to the unique environment, which can lead to compromised functioning of the skeletal and immune systems. However, the mechanisms by which organisms...
2.
Kanai M, Nishino T, Daassi D, Kimura A, Liao C, Shahri Z, et al.
J Immunol
. 2024 Sep;
213(8):1212-1224.
PMID: 39230290
Monocytes and macrophages express the transcription factor MAFB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B) and protect against ischemic acute kidney injury (AKI). However, the mechanism through which MAFB alleviates AKI...
3.
Hayashi T, Sadaki S, Tsuji R, Okada R, Fuseya S, Kanai M, et al.
Stem Cells
. 2024 Jul;
42(9):830-847.
PMID: 38975693
Muscle regeneration depends on muscle stem cell (MuSC) activity. Myogenic regulatory factors, including myoblast determination protein 1 (MyoD), regulate the fate transition of MuSCs. However, the direct target of MYOD...
4.
Yadav M, Ishida M, Gogoleva N, Liao C, Salim F, Kanai M, et al.
Cell Rep
. 2024 Mar;
43(4):113978.
PMID: 38522069
Transcription factor MAFB regulates various homeostatic functions of macrophages. This study explores the role of MAFB in brown adipose tissue (BAT) thermogenesis using macrophage-specific Mafb-deficient (Mafb::LysM-Cre) mice. We find that...
5.
Kawamata T, Wakimoto A, Nishikawa T, Ikezawa M, Hamada M, Inoue Y, et al.
Sci Rep
. 2023 Dec;
13(1):22469.
PMID: 38110459
Natto, known for its high vitamin K content, has been demonstrated to suppress atherosclerosis in large-scale clinical trials through a yet-unknown mechanism. In this study, we used a previously reported...
6.
Hayashi T, Fujita R, Okada R, Hamada M, Suzuki R, Fuseya S, et al.
Commun Biol
. 2023 Apr;
6(1):424.
PMID: 37085700
Skeletal muscle is sensitive to gravitational alterations. We recently developed a multiple artificial-gravity research system (MARS), which can generate gravity ranging from microgravity to Earth gravity (1 g) in space....
7.
Okada R, Fujita S, Suzuki R, Hayashi T, Tsubouchi H, Kato C, et al.
Sci Rep
. 2021 Apr;
11(1):9168.
PMID: 33911096
Spaceflight causes a decrease in skeletal muscle mass and strength. We set two murine experimental groups in orbit for 35 days aboard the International Space Station, under artificial earth-gravity (artificial...
8.
Usui T, Morito N, Shawki H, Sato Y, Tsukaguchi H, Hamada M, et al.
Kidney Int
. 2020 Jul;
98(2):391-403.
PMID: 32622525
Focal segmental glomerulosclerosis (FSGS) is a common cause of steroid-resistant nephrotic syndrome. Spontaneous remission of FSGS is rare and steroid-resistant FSGS frequently progresses to renal failure. Many inheritable forms of...
9.
Kanai M, Jeon H, Ojima M, Nishino T, Usui T, Yadav M, et al.
Biochem Biophys Res Commun
. 2019 Dec;
523(2):452-457.
PMID: 31882119
The transcription factor, MafB, plays important role in the differentiation and functional maintenance of various cells and tissues, such as the inner ear, kidney podocyte, parathyroid gland, pancreatic islet, and...
10.
Tsunakawa Y, Hamada M, Matsunaga Y, Fuseya S, Jeon H, Wakimoto Y, et al.
Exp Anim
. 2018 Oct;
68(1):103-111.
PMID: 30369533
Multicentric carpotarsal osteolysis (MCTO) is a condition involving progressive osteolysis of the carpal and tarsal bones that is associated with glomerular sclerosis and renal failure (MCTO nephropathy). Previous work identified...