Mahmoud Razavian
Overview
Explore the profile of Mahmoud Razavian including associated specialties, affiliations and a list of published articles.
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17
Citations
343
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Recent Articles
1.
Toczek J, Bordenave T, Gona K, Kim H, Beau F, Georgiadis D, et al.
J Med Chem
. 2019 Oct;
62(21):9743-9752.
PMID: 31603669
Matrix metalloproteinase-12 (MMP-12) is highly upregulated in several inflammatory diseases, including abdominal aortic aneurysm (AAA). Here we report four novel Tc-labeled radiotracers derived from a highly selective competitive MMP-12 inhibitor....
2.
Ye Y, Toczek J, Gona K, Kim H, Han J, Razavian M, et al.
Sci Rep
. 2018 Aug;
8(1):11647.
PMID: 30076321
Matrix metalloproteinases (MMPs) are involved in tissue remodeling. Accordingly, MMP inhibitors and related radiolabeled analogs are important tools for MMP-targeted imaging and therapy in a number of diseases. Herein, we...
3.
Toczek J, Ye Y, Gona K, Kim H, Han J, Razavian M, et al.
J Nucl Med
. 2017 Apr;
58(8):1318-1323.
PMID: 28360209
Matrix metalloproteinases (MMPs) play a key role in abdominal aortic aneurysm (AAA) development. Accordingly, MMP-targeted imaging provides important information regarding vessel wall biology in the course of aneurysm development. Given...
4.
Razavian M, Bordenave T, Georgiadis D, Beau F, Zhang J, Golestani R, et al.
Sci Rep
. 2016 Dec;
6:38345.
PMID: 27917892
Matrix metalloproteinase (MMP)-12 plays a key role in the development of aneurysm. Like other members of MMP family, MMP-12 is produced as a proenzyme, mainly by macrophages, and undergoes proteolytic...
5.
Jung J, Razavian M, Kim H, Ye Y, Golestani R, Toczek J, et al.
Sci Rep
. 2016 Sep;
6:32659.
PMID: 27619752
Calcific aortic valve disease (CAVD) is the most common cause of aortic stenosis. Currently, there is no non-invasive medical therapy for CAVD. Matrix metalloproteinases (MMPs) are upregulated in CAVD and...
6.
Bordenave T, Helle M, Beau F, Georgiadis D, Tepshi L, Bernes M, et al.
Bioconjug Chem
. 2016 Aug;
27(10):2407-2417.
PMID: 27564088
In designing new tracers consisting of a small peptide conjugated to a reporter of comparable size, particular attention needs to be paid to the selection of the reporter group, which...
7.
Golestani R, Razavian M, Ye Y, Zhang J, Jung J, Toczek J, et al.
J Nucl Med
. 2016 Jul;
58(1):138-143.
PMID: 27469361
Methods: Lung-specific IL-13 transgenic (Club cell 10-kDa protein [CC10]-IL-13 Tg) mice and wild-type littermates were used in this study. Lung structure, gene expression, and MMP activity were assessed by histology,...
8.
Li X, Jung J, Nie L, Razavian M, Zhang J, Samuel V, et al.
Am J Physiol Heart Circ Physiol
. 2016 Feb;
310(9):H1184-93.
PMID: 26921437
Insulin effects on cell metabolism, growth, and survival are mediated by its binding to, and activation of, insulin receptor. With increasing prevalence of insulin resistance and diabetes there is considerable...
9.
Jung J, Razavian M, Challa A, Nie L, Golestani R, Zhang J, et al.
J Nucl Med
. 2015 Apr;
56(6):933-8.
PMID: 25908827
Unlabelled: Calcific aortic valve disease (CAVD) is the most common cause of aortic stenosis. Matrix metalloproteinases (MMPs) are upregulated in CAVD and contribute to valvular remodeling and calcification. We investigated...
10.
Golestani R, Razavian M, Nie L, Zhang J, Jung J, Ye Y, et al.
Circ Cardiovasc Imaging
. 2015 Jan;
8(1).
PMID: 25550400
Background: Abdominal aortic aneurysm (AAA) rupture risk is currently determined based on size and symptoms. This approach does not address the rupture risk associated with small aneurysms. Given the role...