Mahmoud ElHefnawi
Overview
Explore the profile of Mahmoud ElHefnawi including associated specialties, affiliations and a list of published articles.
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Articles
45
Citations
472
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Recent Articles
1.
Omo-Okhuasuyi A, Jin Y, ElHefnawi M, Chen Y, Flores M
Int J Mol Sci
. 2024 Oct;
25(19).
PMID: 39409014
Diabetic foot ulcers (DFUs) are a severe complication of diabetes mellitus (DM), which often lead to hospitalization and non-traumatic amputations in the United States. Diabetes prevalence estimates in South Texas...
2.
Soliman B, Wen M, Kandil E, El-Agamy B, Gamal-Eldeen A, ElHefnawi M
Pharmaceutics
. 2024 Apr;
16(4).
PMID: 38675155
Currently, there is still a lack of effective carriers with minimal side effects to deliver therapeutic miRNA. Thus, it is crucial to optimize novel drug delivery systems. MiR-375 has proven...
3.
Ibrahim I, Elfiky A, Mahmoud S, ElHefnawi M
J Biomol Struct Dyn
. 2023 Aug;
42(17):9145-9158.
PMID: 37615430
Researchers worldwide are looking for molecules that might disrupt the COVID-19 life cycle. Endoribonuclease, which is responsible for processing viral RNA to avoid detection by the host defense system, and...
4.
Abu-Shahba N, Hegazy E, Khan F, ElHefnawi M
Cancer Inform
. 2023 May;
22:11769351231171743.
PMID: 37200943
Abnormal miRNA expression has been evidenced to be directly linked to HCC initiation and progression. This study was designed to detect possible prognostic, diagnostic, and/or therapeutic miRNAs for HCC using...
5.
Acchioni C, Acchioni M, Mancini F, Amendola A, Marsili G, Tirelli V, et al.
Virology
. 2023 Apr;
583:1-13.
PMID: 37060797
Type I interferon (IFN-I) evasion by Dengue virus (DENV) is key in DENV pathogenesis. The non-structural protein 5 (NS5) antagonizes IFN-I response through the degradation of the signal transducer and...
6.
Tegally H, San J, Cotten M, Moir M, Tegomoh B, Mboowa G, et al.
Science
. 2022 Sep;
378(6615):eabq5358.
PMID: 36108049
Investment in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing in Africa over the past year has led to a major increase in the number of sequences that have been...
7.
Ibrahim I, Elfiky A, Fathy M, Mahmoud S, ElHefnawi M
Sci Rep
. 2022 Aug;
12(1):13337.
PMID: 35922447
Researchers are focused on discovering compounds that can interfere with the COVID-19 life cycle. One of the important non-structural proteins is endoribonuclease since it is responsible for processing viral RNA...
8.
ElHefnawi M, Jo E, Tolba M, Fares M, Yang J, Shahbaaz M, et al.
Virology
. 2022 Mar;
570:9-17.
PMID: 35338891
The repurposing of marketed drugs for new indications is an elegant strategy to quickly and cost-efficiently address unmet medical needs. The hepatitis C virus (HCV) RNA-dependent RNA polymerase (RdRp) has...
9.
Abd-Elsalam S, Ezz M, Gamalel-Din S, Esmat G, Elakel W, ElHefnawi M
J Adv Res
. 2022 Jan;
35:87-97.
PMID: 35024195
Introduction: Esophageal Varices (EVs) is one of the major dangerous complications of liver fibrosis. Upper Gastrointestinal (UGI) Endoscopy is necessary for its diagnosis. Repeated examinations for EVs screening severely burden...
10.
El-Aarag S, Mahmoud A, ElHefnawi M
Int J Biol Macromol
. 2021 Nov;
194:770-780.
PMID: 34826456
The molecular mechanisms underlying the pathogenesis of COVID-19 have not been fully discovered. This study aims to decipher potentially hidden parts of the pathogenesis of COVID-19, potential novel drug targets,...