Mahesh Ramalingam
Overview
Explore the profile of Mahesh Ramalingam including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
325
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Recent Articles
1.
Yoo J, Hwang J, Choi J, Ramalingam M, Jeong H, Jang S, et al.
Heliyon
. 2024 Sep;
10(17):e37081.
PMID: 39295999
Diabetes induces a range of macrovascular and microvascular changes, which lead to significant clinical complications. Although many studies have tried to solve the diabetic problem using drugs, it remains unclear....
2.
Kim D, Hwang J, Yoo J, Choi J, Ramalingam M, Kim S, et al.
PLoS One
. 2024 Sep;
19(9):e0307768.
PMID: 39240883
Traumatic brain injury (TBI) results from sudden accidents, leading to brain damage, subsequent organ dysfunction, and potentially death. Despite extensive studies on rodent TBI models, there is still high variability...
3.
Ramalingam M, Jang S, Kim S, Bai H, Jeong G, Kim B, et al.
Biomedicines
. 2024 Aug;
12(8).
PMID: 39200166
Rotenone (ROT), the most significant rotenoid, which has shown anticancer activity, has also been reported to be toxic to normal cells, inducing Parkinson's disease (PD)-like neuronal loss with aggregation of...
4.
Choi J, Gang S, Ramalingam M, Hwang J, Jeong H, Yoo J, et al.
Mol Cell Biochem
. 2023 Sep;
479(9):2391-2403.
PMID: 37768498
Histone deacetylase (HDAC) inhibitors promote differentiation through post-translational modifications of histones. BML-281, an HDAC6 inhibitor, has been known to prevent tumors, acute dextran sodium sulfate-associated colitis, and lung injury. However,...
5.
Choi J, Hwang J, Ramalingam M, Jeong H, Jang S
BMC Neurosci
. 2023 May;
24(1):28.
PMID: 37127577
Histone deacetylase (HDAC) inhibitors affect cell homeostasis, gene expression, and cell cycle progression and promote cell terminal differentiation or apoptosis. However, the effect of HDAC inhibition on SH-SY5Y cells, which...
6.
Ramalingam M, Jang S, Hwang J, Kim B, Cho H, Kim E, et al.
Int J Mol Sci
. 2023 Mar;
24(6).
PMID: 36982698
Mesenchymal stem cells (MSCs) have therapeutic effects on neurodegenerative diseases (NDDs) known by their secreted molecules, referred to as the "secretome". The mitochondrial complex I inhibitor, rotenone (ROT), reproduces α-synuclein...
7.
Neuroprotective Effects of a Wnt Antagonist in Quinolinic Acid-Induced Excitotoxicity in N18D3 Cells
Hwang J, Park J, Ramalingam M, Kim B, Jeong H, Jang S
Cell Mol Biol (Noisy-le-grand)
. 2023 Feb;
68(8):167-172.
PMID: 36800814
Excessive stimulation of the quinolinic acid induces neuronal cell death and is implicated in developing several neurodegenerative diseases. This study investigated whether a Wnt5a antagonist plays a neuroprotective role by...
8.
Soni K, Hwang J, Ramalingam M, Kim C, Kim B, Jeong H, et al.
Int J Mol Sci
. 2023 Jan;
24(2).
PMID: 36674822
A spinal cord injury (SCI) is the devastating trauma associated with functional deterioration due to apoptosis. Most laboratory SCI models are generated by a direct impact on an animal's spinal...
9.
Ramalingam M, Jeong H, Hwang J, Cho H, Kim B, Kim E, et al.
Int J Mol Sci
. 2022 Apr;
23(8).
PMID: 35457010
Rotenone (ROT) inhibits mitochondrial complex I, leading to reactive oxygen species formation, which causes neurodegeneration and alpha-synuclein (α-syn) aggregation and, consequently, Parkinson's disease. We previously found that a neurogenic differentiated...
10.
Ramalingam M, Jang S, Jeong H
Int J Mol Sci
. 2021 Mar;
22(5).
PMID: 33652595
Parkinson's disease (PD) is an age-related neurodegenerative disease (NDD) characterized by the degenerative loss of dopaminergic neurons in the substantia nigra along with aggregation of α-synuclein (α-syn). Neurogenic differentiation of...