Mahesh Jayaram
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Explore the profile of Mahesh Jayaram including associated specialties, affiliations and a list of published articles.
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33
Citations
138
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Recent Articles
1.
Vaziri N, Shutt T, Karim W, Raedler T, Pantelis C, Thomas N, et al.
Mol Psychiatry
. 2025 Feb;
PMID: 39962181
Clozapine is the only approved pharmacotherapy for treatment-resistant schizophrenia. However, widespread utilization of clozapine is constrained due to the potential for severe adverse effects, including myocarditis. Multiple mechanisms have been...
2.
Wimalasiri I, Jain N, Jayaram M
BMJ Case Rep
. 2024 Sep;
17(9).
PMID: 39289031
Hereditary angioedema (HAE) is a rare autosomal dominant disorder caused by the deficiency or dysfunction of C1 esterase inhibitors. We present a case of a female in her 50s with...
3.
Ravanfar P, Syeda W, Jayaram M, Rushmore R, Moffat B, Lin A, et al.
Schizophrenia (Heidelb)
. 2022 Oct;
8(1):86.
PMID: 36289238
Brain iron is central to dopaminergic neurotransmission, a key component in schizophrenia pathology. Iron can also generate oxidative stress, which is one proposed mechanism for gray matter volume reduction in...
4.
Syeda W, Wannan C, Merritt A, Raghava J, Jayaram M, Velakoulis D, et al.
Neuroimage Clin
. 2022 Jun;
35:103064.
PMID: 35689976
Background: Brain structural alterations and cognitive dysfunction are independent predictors for poor clinical outcome in schizophrenia, and the associations between these domains remains unclear. We employed a novel, multiblock partial...
5.
Narang A, Lacaze P, Ronaldson K, McNeil J, Jayaram M, Thomas N, et al.
Pharmacogenomics J
. 2022 Apr;
22(3):173-179.
PMID: 35461379
One of the concerns limiting the use of clozapine in schizophrenia treatment is the risk of rare but potentially fatal myocarditis. Our previous genome-wide association study and human leucocyte antigen...
6.
Eratne D, Janelidze S, Malpas C, Loi S, Walterfang M, Merritt A, et al.
Aust N Z J Psychiatry
. 2022 Feb;
56(10):1295-1305.
PMID: 35179048
Objective: Schizophrenia, a complex psychiatric disorder, is often associated with cognitive, neurological and neuroimaging abnormalities. The processes underlying these abnormalities, and whether a subset of people with schizophrenia have a...
7.
Jayaram M, Shields G, Buisman-Pijlman F
Curr Opin Psychiatry
. 2021 Aug;
34(5):491-496.
PMID: 34421112
Purpose Of Review: Global burden of mental illness remains at an all-time high and provision of timely good quality care is a challenge globally. Current methods of medical and post-graduate...
8.
Hicks A, Clay F, Hopwood M, James A, Perry L, Jayaram M, et al.
J Neurotrauma
. 2020 Oct;
38(5):519-528.
PMID: 33045912
After a traumatic brain injury (TBI), many persons experience significant and debilitating problems with anxiety. The aim of this systematic review was to critically evaluate the evidence regarding efficacy of...
9.
Pantelis C, Jayaram M, Hannan A, Wesselingh R, Nithianantharajah J, Wannan C, et al.
Aust N Z J Psychiatry
. 2020 Oct;
55(8):750-762.
PMID: 32998512
Although COVID-19 is predominantly a respiratory disease, it is known to affect multiple organ systems. In this article, we highlight the impact of SARS-CoV-2 (the coronavirus causing COVID-19) on the...
10.
Lewis M, Chondros P, Mihalopoulos C, Lee Y, Gunn J, Harvey C, et al.
Contemp Clin Trials
. 2020 Sep;
97:106143.
PMID: 32931919
Background: Cardiovascular disease (CVD) accounts for 40% of the excess mortality identified in people with severe mental illness (SMI). Modifiable CVD risk factors are higher and can be exacerbated by...