Magnus J Hansson
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Explore the profile of Magnus J Hansson including associated specialties, affiliations and a list of published articles.
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55
Citations
1286
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Recent Articles
1.
Pizzamiglio C, Stefanetti R, McFarland R, Thomas N, Ransley G, Hugerth M, et al.
Brain
. 2024 Dec;
148(1):39-46.
PMID: 39657714
Over the past two decades there has been increased interest in orphan drug development for rare diseases. However, hurdles to clinical trial design for these disorders remain. This phase 1a/1b...
2.
Westerlund E, Marelsson S, Karlsson M, Sjovall F, Chamkha I, Asander Frostner E, et al.
Heliyon
. 2024 Mar;
10(5):e26745.
PMID: 38439844
There is a growing interest for the possibility of using peripheral blood cells (including platelets) as markers for mitochondrial function in less accessible tissues. Only a few studies have examined...
3.
Hansson M, Elmer E
Neurotherapeutics
. 2023 Aug;
20(6):1482-1495.
PMID: 37561274
Drug development in traumatic brain injury (TBI) has been impeded by the complexity and heterogeneity of the disease pathology, as well as limited understanding of the secondary injury cascade that...
4.
Piel S, Janowska J, Ward J, McManus M, Jose J, Starr J, et al.
Sci Rep
. 2022 Nov;
12(1):20329.
PMID: 36434021
Pesticides account for hundreds of millions of cases of acute poisoning worldwide each year, with organophosphates (OPs) being responsible for the majority of all pesticide-related deaths. OPs inhibit the enzyme...
5.
Piel S, Janowska J, Ward J, McManus M, Aronowitz D, Janowski P, et al.
Mol Cell Biochem
. 2022 Oct;
478(6):1231-1244.
PMID: 36282352
Sodium fluoroacetate (FA) is a metabolic poison that systemically inhibits the tricarboxylic acid (TCA) cycle, causing energy deficiency and ultimately multi-organ failure. It poses a significant threat to society because...
6.
Grins E, Ederoth P, Bjursten H, Dardashti A, Bronden B, Metzsch C, et al.
J Cardiothorac Vasc Anesth
. 2021 Dec;
36(7):1985-1994.
PMID: 34969566
Objectives: The augmented inflammatory response to cardiac surgery is a recognized cause of postoperative acute kidney injury. The present study aimed to investigate the effects of preoperative cyclosporine treatment on...
7.
Avram V, Chamkha I, Asander-Frostner E, Ehinger J, Timar R, Hansson M, et al.
Int J Mol Sci
. 2021 Jan;
22(1).
PMID: 33401621
Statins are the cornerstone of lipid-lowering therapy. Although generally well tolerated, statin-associated muscle symptoms (SAMS) represent the main reason for treatment discontinuation. Mitochondrial dysfunction of complex I has been implicated...
8.
Karlsson M, Yang Z, Chawla S, Delso N, Pukenas B, Elmer E, et al.
J Neurotrauma
. 2020 Nov;
38(13):1870-1878.
PMID: 33191835
All phase III trials evaluating medical treatments for traumatic brain injury (TBI), performed to date, have failed. To facilitate future success there is a need for novel outcome metrics that...
9.
Kristiansson A, Davidsson S, Johansson M, Piel S, Elmer E, Hansson M, et al.
Int J Mol Sci
. 2020 Aug;
21(16).
PMID: 32823731
Oxidative stress is associated with many renal disorders, both acute and chronic, and has also been described to contribute to the disease progression. Therefore, oxidative stress is a potential therapeutic...
10.
Piel S, Chamkha I, Dehlin A, Ehinger J, Sjovall F, Elmer E, et al.
PLoS One
. 2020 Apr;
15(4):e0231173.
PMID: 32251487
Acetaminophen is one of the most common over-the-counter pain medications used worldwide and is considered safe at therapeutic dose. However, intentional and unintentional overdose accounts for up to 70% of...