Magdalena Kotowska
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Explore the profile of Magdalena Kotowska including associated specialties, affiliations and a list of published articles.
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12
Citations
181
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Recent Articles
1.
Kotowska M, Wenecki M, Bednarz B, Ciekot J, Paslawski W, Buhl T, et al.
Appl Microbiol Biotechnol
. 2024 Dec;
108(1):531.
PMID: 39656307
Coelimycin (CPK) producer Streptomyces coelicolor A3(2) is a well-established model for the genetic studies of bacteria from the genus Streptomyces, renowned for their ability to produce a plethora of antibiotics...
2.
Pawlik K, Zelkowski M, Biernacki M, Litwinska K, Jaworski P, Kotowska M
Int J Mol Sci
. 2021 Nov;
22(21).
PMID: 34769298
bacteria produce a plethora of secondary metabolites including the majority of medically important antibiotics. The onset of secondary metabolism is correlated with morphological differentiation and controlled by a complex regulatory...
3.
Bednarz B, Millan-Oropeza A, Kotowska M, Swiat M, Quispe Haro J, Henry C, et al.
Front Microbiol
. 2021 Apr;
12:616050.
PMID: 33897632
Many microbial specialized metabolites are industrially relevant agents but also serve as signaling molecules in intra-species and even inter-kingdom interactions. In the antibiotic-producing , members of the SARP ( antibiotic...
4.
Kotowska M, Swiat M, Zarba-Paslawska J, Jaworski P, Pawlik K
Front Microbiol
. 2019 Jul;
10:1451.
PMID: 31297104
Bacteria from the genus have been long exploited as the most prolific producers of antibiotics, other secondary metabolites and enzymes. They are important members of soil microbial communities that can...
5.
Bednarz B, Kotowska M, Pawlik K
Appl Microbiol Biotechnol
. 2019 Jun;
103(16):6423-6434.
PMID: 31250060
Despite being a yellow pigment visible to the human eye, coelimycin (CPK) remained to be an undiscovered secondary metabolite for over 50 years of Streptomyces research. Although the function of...
6.
Kotowska M, Pawlik K
Appl Microbiol Biotechnol
. 2014 Aug;
98(18):7735-46.
PMID: 25081554
A large number of antibiotics and other industrially important microbial secondary metabolites are synthesized by polyketide synthases (PKSs) and nonribosomal peptide synthetases (NRPSs). These multienzymatic complexes provide an enormous flexibility...
7.
Kotowska M, Ciekot J, Pawlik K
Acta Biochim Pol
. 2014 Mar;
61(1):141-7.
PMID: 24660171
Type II thioesterases were shown to maintain efficiency of modular type I polyketide synthases and nonribosomal peptide synthetases by removing acyl residues blocking extension modules. We found that thioesterase ScoT...
8.
Pawlik K, Kotowska M, Kolesinski P
J Mol Microbiol Biotechnol
. 2010 Oct;
19(3):147-51.
PMID: 20924201
Streptomyces coelicolor A3(2) is an extensively studied model organism for the genetic studies of Streptomycetes - a genus known for the production of a vast number of bioactive compounds and...
9.
Kotowska M, Pawlik K, Smulczyk-Krawczyszyn A, Bartosz-Bechowski H, Kuczek K
Appl Environ Microbiol
. 2008 Dec;
75(4):887-96.
PMID: 19074611
Type II thioesterases (TE IIs) were shown to maintain the efficiency of polyketide synthases (PKSs) by removing acyl residues blocking extension modules. However, the substrate specificity and kinetic parameters of...
10.
Pawlik K, Kotowska M, Chater K, Kuczek K, Takano E
Arch Microbiol
. 2006 Sep;
187(2):87-99.
PMID: 17009021
The chromosome of Streptomyces coelicolor A3(2), a model organism for the genus Streptomyces, contains a cryptic type I polyketide synthase (PKS) gene cluster which was revealed when the genome was...