Madhusoodana P Nambiar
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Explore the profile of Madhusoodana P Nambiar including associated specialties, affiliations and a list of published articles.
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73
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931
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Recent Articles
1.
Arun P, Oguntayo S, Van Albert S, Gist I, Wang Y, Nambiar M, et al.
Neurosci Lett
. 2015 Oct;
609:152-8.
PMID: 26483321
Dephosphorylation of phosphorylated Tau (pTau) protein, which is essential for the preservation of neuronal microtubule assemblies and for protection against trauma-induced tauopathy and chronic traumatic encephalopathy (CTE), is primarily achieved...
2.
Valiyaveettil M, Alamneh Y, Wang Y, Arun P, Oguntayo S, Wei Y, et al.
Brain Res
. 2014 Jan;
1549:32-41.
PMID: 24412202
Repeated blast exposures commonly induce traumatic brain injury (TBI) characterized by diffuse axonal injury (DAI). We hypothesized that degradation of cytoskeletal proteins in the brain can lead to DAI, and...
3.
Wang Y, Arun P, Wei Y, Oguntayo S, Gharavi R, Valiyaveettil M, et al.
J Neurotrauma
. 2013 Oct;
31(5):498-504.
PMID: 24074345
The pathophysiology of blast-induced traumatic brain injury (TBI) and subsequent behavioral deficits are not well understood. Unraveling the mechanisms of injury is critical to derive effective countermeasures against this form...
4.
Arun P, Abu-Taleb R, Oguntayo S, Tanaka M, Wang Y, Valiyaveettil M, et al.
Neurosci Lett
. 2013 Aug;
552:87-91.
PMID: 23933206
Glial fibrillary acidic protein (GFAP), a protein enriched in astrocytes, and Tau, a protein abundant in neuronal microtubules, are being widely studied as biomarkers of brain injury, and persistent severity-dependent...
5.
Arun P, Abu-Taleb R, Oguntayo S, Wang Y, Valiyaveettil M, Long J, et al.
J Neurotrauma
. 2013 Apr;
30(19):1645-51.
PMID: 23600763
Use of improvised explosive devices has significantly increased the incidence of traumatic brain injury (TBI) and associated neuropsychiatric deficits in the recent wars in Iraq and Afghanistan. Acute deleterious effects...
6.
Arun P, Abu-Taleb R, Valiyaveettil M, Wang Y, Long J, Nambiar M
Neurosci Res
. 2013 Mar;
76(1-2):98-100.
PMID: 23511555
Blast-induced traumatic brain injury (TBI) and subsequent neurobehavioral deficits are major disabilities suffered by the military and civilian population worldwide. Rigorous scientific research is underway to understand the mechanism of...
7.
Gunosewoyo H, Tipparaju S, Pieroni M, Wang Y, Doctor B, Nambiar M, et al.
Bioorg Med Chem Lett
. 2013 Feb;
23(5):1544-7.
PMID: 23395652
Chemical warfare nerve agents such as soman exert their toxic effects through an irreversible inhibition of acetylcholinesterase (AChE) and subsequently glutamatergic function, leading to uncontrolled seizures. The natural alkaloid (-)-huperzine...
8.
Valiyaveettil M, Alamneh Y, Wang Y, Arun P, Oguntayo S, Wei Y, et al.
Neurosci Lett
. 2013 Feb;
539:1-6.
PMID: 23370286
Blast-induced traumatic brain injury is complex and involves multiple factors including systemic pathophysiological factors in addition to direct brain injuries. We hypothesize that systemic activation of platelets/leukocytes plays a major...
9.
Valiyaveettil M, Alamneh Y, Miller S, Hammamieh R, Wang Y, Arun P, et al.
J Rehabil Res Dev
. 2013 Jan;
49(7):1153-62.
PMID: 23341286
The mechanisms of central auditory processing involved in auditory/vestibular injuries and subsequent tinnitus and hearing loss in Active Duty servicemembers exposed to blast are not currently known. We analyzed the...
10.
De Gasperi R, Gama Sosa M, Kim S, Steele J, Shaughness M, Maudlin-Jeronimo E, et al.
Front Neurol
. 2012 Dec;
3:177.
PMID: 23267342
Blast-induced traumatic brain injury (TBI) has been a major cause of morbidity and mortality in the conflicts in Iraq and Afghanistan. How the primary blast wave affects the brain is...