Madeleine Eunice Betouke Ongwe
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Explore the profile of Madeleine Eunice Betouke Ongwe including associated specialties, affiliations and a list of published articles.
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7
Citations
20
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Recent Articles
1.
Juul-Kristensen T, Thiesen C, Wulff Haurum L, Keller J, Lendamba R, Zoleko Manego R, et al.
Sensors (Basel)
. 2025 Jan;
24(24.
PMID: 39771686
Malaria poses a serious global health problem, with half the world population being at risk. Regular screening is crucial for breaking the transmission cycle and combatting the disease spreading. However,...
2.
Betouke Ongwe M, Mouwenda Y, Manurung M, Heieis G, Azimi S, Adegnika A, et al.
Eur J Immunol
. 2024 Jun;
54(9):e2451029.
PMID: 38873882
Cellular metabolism is a key determinant of immune cell function. Here we found that CD14 monocytes from Sub-Saharan Africans produce higher levels of IL-10 following TLR-4 stimulation and are bioenergetically...
3.
Mouwenda Y, Jochems S, van Unen V, Betouke Ongwe M, de Steenhuijsen Piters W, Stam K, et al.
JCI Insight
. 2024 May;
9(9).
PMID: 38716733
Vaccination of malaria-naive volunteers with a high dose of Plasmodium falciparum sporozoites chemoattenuated by chloroquine (CQ) (PfSPZ-CVac [CQ]) has previously demonstrated full protection against controlled human malaria infection (CHMI). However,...
4.
Betouke Ongwe M, Kohler I, Manurung M, Verhoeven A, Derks R, Janse J, et al.
Metabolites
. 2022 Dec;
12(12).
PMID: 36557262
The interaction of malaria parasites with their human host is extensively studied, yet only few studies reported how infection affects urinary metabolite profiles and how this is associated with immunity....
5.
Betouke Ongwe M, Mouwenda Y, Stam K, Kremsner P, Lell B, Diemert D, et al.
PLoS One
. 2022 Sep;
17(9):e0275013.
PMID: 36155987
Metabolomics provides a powerful tool to study physiological changes in response to various perturbations such as vaccination. We explored whether metabolomic changes could be seen after vaccination in a phase...
6.
Manurung M, de Jong S, Kruize Y, Mouwenda Y, Betouke Ongwe M, Josiane Honkpehedji Y, et al.
Sci Rep
. 2022 Aug;
12(1):13303.
PMID: 35922467
Controlled human malaria infection (CHMI) using cryopreserved non-attenuated Plasmodium falciparum sporozoites (PfSPZ) offers a unique opportunity to investigate naturally acquired immunity (NAI). By analyzing blood samples from 5 malaria-naïve European...
7.
de Jong S, van Unen V, Manurung M, Stam K, Goeman J, Jochems S, et al.
Nat Immunol
. 2021 Apr;
22(5):654-665.
PMID: 33888898
Controlled human infections provide opportunities to study the interaction between the immune system and malaria parasites, which is essential for vaccine development. Here, we compared immune signatures of malaria-naive Europeans...