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Madalina Dumitrescu

Explore the profile of Madalina Dumitrescu including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 139
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Recent Articles
1.
Florea G, Tudorache I, Fuior E, Ionita R, Dumitrescu M, Fenyo I, et al.
Biomedicines . 2022 Jul; 10(7). PMID: 35884883
Apolipoprotein A-II (apoA-II) is the second most abundant apolipoprotein in high-density lipoprotein (HDL) particles, playing an important role in lipid metabolism. Human and murine apoA-II proteins have dissimilar properties, partially...
2.
Tudorache I, Bivol V, Dumitrescu M, Fenyo I, Simionescu M, Gafencu A
Pharmacol Rep . 2022 Jul; 74(4):684-695. PMID: 35790693
Background: Apolipoprotein E (apoE) is an anti-atherosclerotic protein associated with almost all plasma lipoproteins. Fullerenol (Full-OH) contains the fullerene hydrophobic cage and several hydroxyl groups that could be derivatized to...
3.
Dumitrescu M, Constantin A, Nemecz A, Dragan E, Popov L, Tanko G
Rom J Morphol Embryol . 2022 Mar; 62(3):713-721. PMID: 35263399
Hypertension-induced left ventricular hypertrophy evolves initially as an adaptive response meant to minimize ventricular wall stress. The mechanisms involved in the preservation of the cardiac function during the "compensatory" phase...
4.
Vacaru A, Mazilu A, Dumitrescu M, Fenyo I, Gafencu A, Vacaru A
Int J Mol Sci . 2022 Jan; 23(1). PMID: 35008964
Allogeneic hematopoietic cell transplantation (allo-HCT) has the potential to cure malignant and non-malignant hematological disorders, but because of the serious side effects of this intervention its applications are limited to...
5.
Dumitrescu M, Trusca V, Fenyo I, Gafencu A
J Vis Exp . 2021 Jun; (172). PMID: 34180881
Adenoviral transduction has the advantage of a strong and transient induction of the expression of the gene of interest into a broad variety of cell types and organs. However, recombinant...
6.
Dumitrescu M, Vacaru A, Trusca V, Fenyo I, Ionita R, Gafencu A
Int J Mol Sci . 2021 Jan; 22(2). PMID: 33435318
Adenoviral vectors are important vehicles for delivering therapeutic genes into mammalian cells. However, the yield of the adenoviral transduction of murine mesenchymal stromal cells (MSC) is low. Here, we aimed...
7.
Vacaru A, Dumitrescu M, Vacaru A, Fenyo I, Ionita R, Gafencu A, et al.
Int J Mol Sci . 2021 Jan; 22(1). PMID: 33396269
Mesenchymal stromal cells (MSC) display several mechanisms of action that may be harnessed for therapeutic purposes. One of their most attractive features is their immunomodulatory activity that has been extensively...
8.
Dumitrescu M, Trusca V, Savu L, Stancu I, Ratiu A, Simionescu M, et al.
Int J Mol Sci . 2020 Aug; 21(17). PMID: 32825521
Fas ligand (First apoptosis signal ligand, FasL, also known as CD95L) is the common executioner of apoptosis within the tumor necrosis factor (TNF) superfamily. We aimed to induce functional FasL...
9.
Trusca V, Dumitrescu M, Fenyo I, Tudorache I, Simionescu M, Gafencu A
Int J Mol Sci . 2019 Dec; 20(24). PMID: 31842455
Apolipoprotein A-I (apoA-I) is the major protein component of high-density lipoproteins (HDL), mediating many of its atheroprotective properties. Increasing data reveal the pro-atherogenic effects of bisphenol A (BPA), one of...
10.
Nemecz M, Constantin A, Dumitrescu M, Alexandru N, Filippi A, Tanko G, et al.
Front Pharmacol . 2019 Feb; 9:1554. PMID: 30719005
In this study, we aimed to identify the mechanisms underlying the different effects of palmitic acid and oleic acid on human pancreatic beta cell function. To address this problem, the...