Mackenzie M Johnson
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Explore the profile of Mackenzie M Johnson including associated specialties, affiliations and a list of published articles.
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8
Citations
23
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Recent Articles
1.
Sung K, Johnson M, Dumm W, Simon N, Haddox H, Fukuyama J, et al.
bioRxiv
. 2024 Dec;
PMID: 39651125
Somatic hypermutation (SHM) is the diversity-generating process in antibody affinity maturation. Probabilistic models of SHM are needed for analyzing rare mutations, for understanding the selective forces guiding affinity maturation, and...
2.
Cole J, Scott C, Johnson M, Golightly P, Carlson J, Ming M, et al.
Proc Natl Acad Sci U S A
. 2024 Sep;
121(39):e2412315121.
PMID: 39302970
Sex-differential selection (SDS), which occurs when the fitness effects of alleles differ between males and females, can have profound impacts on the maintenance of genetic variation, disease risk, and other...
3.
Johnson M, Hockenberry A, McGuffie M, Vieira L, Wilke C
Mol Biol Evol
. 2023 Aug;
40(9).
PMID: 37619989
The most highly expressed genes in microbial genomes tend to use a limited set of synonymous codons, often referred to as "preferred codons." The existence of preferred codons is commonly...
4.
Johnson M, Hockenberry A, McGuffie M, Vieira L, Wilke C
bioRxiv
. 2023 Mar;
PMID: 36993177
The most highly expressed genes in microbial genomes tend to use a limited set of synonymous codons, often referred to as "preferred codons." The existence of preferred codons is commonly...
5.
Klein B, Holmer L, Smith K, Johnson M, Swain A, Stolp L, et al.
Commun Biol
. 2021 Dec;
4(1):1352.
PMID: 34857859
Protein-protein interaction (PPI) networks represent complex intra-cellular protein interactions, and the presence or absence of such interactions can lead to biological changes in an organism. Recent network-based approaches have shown...
6.
Johnson M, Wilke C
J Mol Evol
. 2020 Nov;
88(10):731-741.
PMID: 33230664
In many applications of evolutionary inference, a model of protein evolution needs to be fitted to the amino acid variation at individual sites in a multiple sequence alignment. Most existing...
7.
Teufel A, Johnson M, Laurent J, Kachroo A, Marcotte E, Wilke C
Mol Biol Evol
. 2018 Nov;
35(12):e1.
PMID: 30445614
No abstract available.
8.
Teufel A, Johnson M, Laurent J, Kachroo A, Marcotte E, Wilke C
Mol Biol Evol
. 2018 Nov;
36(2):304-314.
PMID: 30428072
Gene duplication is seen as a major source of structural and functional divergence in genome evolution. Under the conventional models of sub or neofunctionalization, functional changes arise in one of...