MacKenzie L Bolen
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Explore the profile of MacKenzie L Bolen including associated specialties, affiliations and a list of published articles.
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6
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2
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Recent Articles
1.
Jernigan J, Staley H, Baty Z, Bolen M, Gomes B, Holt J, et al.
J Neuroinflammation
. 2025 Feb;
22(1):49.
PMID: 39994765
Regulator of G-protein signaling 10 (RGS10), a key homeostatic regulator of immune cells, has been implicated in multiple diseases associated with aging and chronic inflammation including Parkinson's Disease (PD). Interestingly,...
2.
Bolen M, Gomes B, Gill B, Menees K, Staley H, Jernigan J, et al.
Neurobiol Dis
. 2025 Jan;
207:106794.
PMID: 39805368
Parkinson's Disease (PD) is a multisystem disorder in which dysregulated neuroimmune crosstalk and inflammatory relay via the gut-blood-brain axis have been implicated in PD pathogenesis. Although alterations in circulating inflammatory...
3.
Jernigan J, Staley H, Baty Z, Bolen M, Gomes B, Holt J, et al.
bioRxiv
. 2024 Nov;
PMID: 39554164
Regulator of G-protein signaling 10 (RGS10), a key homeostatic regulator of immune cells, has been implicated in multiple diseases associated with aging and chronic inflammation including Parkinson's Disease (PD). Interestingly,...
4.
Staley H, Jernigan J, Bolen M, Titus A, Neighbarger N, Cole C, et al.
J Neuroinflammation
. 2024 Nov;
21(1):280.
PMID: 39487477
Genome-wide association studies have identified a protective mutation in the phospholipase C gamma 2 (PLCG2) gene which confers protection against Alzheimer's disease (AD)-associated cognitive decline. Therefore, PLCG2, which is primarily...
5.
Merchak A, Bolen M, Tansey M, Menees K
Neurotherapeutics
. 2024 Oct;
21(6):e00476.
PMID: 39482179
The complex network of factors that contribute to neurodegeneration have hampered the discovery of effective preventative measures. While much work has focused on brain-first therapeutics, it is becoming evident that...
6.
Bolen M, Gomes B, Gill B, Menees K, Staley H, Jernigan J, et al.
bioRxiv
. 2024 Sep;
PMID: 39229100
Parkinson's Disease (PD) is a multisystem disorder in which dysregulated neuroimmune crosstalk and inflammatory relay via the gut-blood-brain axis have been implicated in PD pathogenesis. Although alterations in circulating inflammatory...
7.
Rodrigues M, Bolen M, Blackmer-Raynolds L, Schwartz N, Chang J, Tansey M, et al.
Neurobiol Dis
. 2024 Apr;
196:106511.
PMID: 38670277
Emerging evidence indicates that high-fat, high carbohydrate diet (HFHC) impacts central pathological features of Alzheimer's disease (AD) across both human incidences and animal models. However, the mechanisms underlying this association...
8.
Rodrigues M, Bolen M, Blackmer-Raynolds L, Schwartz N, Chang J, Tansey M, et al.
bioRxiv
. 2024 Mar;
PMID: 38464096
Emerging evidence indicates that high-fat, high carbohydrate diet (HFHC) impacts central pathological features of Alzheimer's disease (AD) across both human incidences and animal models. However, the mechanisms underlying this association...