Machteld J van Amerongen
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Explore the profile of Machteld J van Amerongen including associated specialties, affiliations and a list of published articles.
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13
Citations
644
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Recent Articles
1.
Musa G, Cazorla-Vazquez S, van Amerongen M, Stemmler M, Eckstein M, Hartmann A, et al.
Ann N Y Acad Sci
. 2019 Jun;
1456(1):96-108.
PMID: 31215653
GPR126 (ADGRG6) is an adhesion G protein-coupled receptor that plays an important role in a variety of tissues/organs, such as heart, sciatic nerve, cartilage, and ear. Moreover, GPR126 (ADGRG6) mutations...
2.
Patra C, van Amerongen M, Ghosh S, Ricciardi F, Sajjad A, Novoyatleva T, et al.
Proc Natl Acad Sci U S A
. 2013 Oct;
110(42):16898-903.
PMID: 24082093
Despite their abundance and multiple functions in a variety of organ systems, the function and signaling mechanisms of adhesion G protein-coupled receptors (GPCRs) are poorly understood. Adhesion GPCRs possess large...
3.
Patra C, Diehl F, Ferrazzi F, van Amerongen M, Novoyatleva T, Schaefer L, et al.
Development
. 2011 Sep;
138(20):4499-509.
PMID: 21937601
The extracellular matrix is crucial for organogenesis. It is a complex and dynamic component that regulates cell behavior by modulating the activity, bioavailability and presentation of growth factors to cell...
4.
Diehl F, Brown M, van Amerongen M, Novoyatleva T, Wietelmann A, Harriss J, et al.
PLoS One
. 2010 Mar;
5(3):e9748.
PMID: 20305823
Chromatin modifying enzymes play a critical role in cardiac differentiation. Previously, it has been shown that the targeted deletion of the histone methyltransferase, Smyd1, the founding member of the SET...
5.
van Amerongen M, Diehl F, Novoyatleva T, Patra C, Engel F
Cardiovasc Res
. 2009 Dec;
86(1):92-102.
PMID: 19955219
Aims: Although the fundamental role of the E2F transcription factor family in cell proliferation is well established, the specific function of E2F4 is unclear. On the basis of findings from...
6.
Novoyatleva T, Diehl F, van Amerongen M, Patra C, Ferrazzi F, Bellazzi R, et al.
Cardiovasc Res
. 2009 Nov;
85(4):681-90.
PMID: 19887380
Aims: Proliferation of mammalian cardiomyocytes stops during the first weeks after birth, preventing the heart from regenerating after injury. Recently, several studies have indicated that induction of cardiomyocyte proliferation can...
7.
van Amerongen M, Engel F
J Cell Mol Med
. 2008 Jul;
12(6A):2233-44.
PMID: 18662194
The human heart does not regenerate. Instead, following injury, human hearts scar. The loss of contractile tissue contributes significantly to morbidity and mortality. In contrast to humans, zebrafish and newts...
8.
van Amerongen M, Harmsen M, Petersen A, Popa E, van Luyn M
Cardiovasc Pathol
. 2007 Dec;
17(1):23-31.
PMID: 18160057
Introduction: Although traditionally adult cardiomyocytes are thought to be unable to divide, recent observations provide evidence for cardiomyocyte proliferation after myocardial injury. Myocardial cryoinjury has been shown to be followed...
9.
van Amerongen M, Harmsen M, van Rooijen N, Petersen A, van Luyn M
Am J Pathol
. 2007 Feb;
170(3):818-29.
PMID: 17322368
Macrophages have been suggested to be beneficial for myocardial wound healing. We investigated the role of macrophages in myocardial wound healing by inhibition of macrophage infiltration after myocardial injury. We...
10.
Luttikhuizen D, van Amerongen M, de Feijter P, Petersen A, Harmsen M, van Luyn M
Biomaterials
. 2006 Aug;
27(34):5763-70.
PMID: 16934325
The foreign body reaction (FBR) differs between subcutaneously and supra-epicardially implanted materials. We hypothesize that this is a result of differences in cytokine, chemokine and matrix metalloproteinase (MMP) dynamics. Therefore...